Prosthetic joint infections: single versus combination therapy

January 25, 2012 at 6:51 pm Leave a comment

Journal of Antimicrobial and Chemotherapy January 2010 V.65 N.1 P.18-23

Abstract

Prosthetic joint replacement is increasingly used to alleviate pain and increase mobility. Bone and joint infections remain a therapeutic dilemma for healthcare providers in all fields. Antimicrobial agents combined with appropriate surgical techniques play a vital role in eradicating infections associated with prosthetic joints. The question still remains whether monotherapy or combination therapy is effective in this situation because there is a paucity of well-defined comparative studies. We reviewed in vitro and in vivo studies evaluating the effectiveness of various antimicrobial agents either as single agents or in combination.

abstract

http://jac.oxfordjournals.org/content/65/1/18.abstract

PDF

http://jac.oxfordjournals.org/content/65/1/18.full.pdf+html

 

Entry filed under: Antimicrobianos, Bacterias, Bacteriemias, Infecciones osteo-articulares-musculares, Infecciones relacionadas a prótesis, Metodos diagnosticos. Tags: .

Treatment of acute hepatitis C in HIV infection The diagnosis and management of prosthetic joint infections

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