Methicillin-Resistant Staphylococcus aureus Colonization, Behavioral Risk Factors, and Skin and Soft-Tissue Infection at an Ambulatory Clinic Serving a Large Population of HIV-Infected Men Who Have Sex with Men

June 21, 2009 at 8:22 pm Leave a comment

Clinical Infectious Diseases  July 1, 2009  V.49  N.1  p.118–121


John D. Szumowski,1 Kenneth M. Wener,3 Howard S. Gold,1 Michael Wong,1 Lata Venkataraman,1

Carrie A. Runde,4 Daniel E. Cohen,5 Kenneth H. Mayer,2,6,7 and Sharon B. Wright1

1Division of Infectious Diseases, Department of Medicine, Beth Israel Deaconess Medical Center, and 2Fenway Community Health, Boston, and 3Department of Infectious Diseases, Division of Medicine, Lahey Clinic, Burlington, Massachusetts; 4Bastyr University, Seattle, Washington; 5Abbott Laboratories, Abbott Park, Illinois and Departments of 6Medicine and 7Community Health, Brown University School of Medicine, Providence, Rhode Island

We conducted a prospective cohort study of 795 outpatients, many of whom were human immunodeficiency virus–infected men who have sex with men, to characterize risk of skin and soft-tissue infection (SSTI) associated with methicillin-resistant Staphylococcus aureus (MRSA) nares and perianal colonization. Multivariate analysis revealed that perianal colonization, drug use, and prior SSTIs were strongly associated with development of an SSTI. Of the patients who were colonized with MRSA at study entry, 36.7% developed an SSTI during the ensuing 12 months, compared with 8.1% of persons who were not colonized with MRSA.


Entry filed under: Bacterias, Epidemiología, HIV/SIDA, HIV/SIDA Complicaciones, HIV/SIDA Trastornos Piel y Tej Blandos, Infecciones en piel y tej blandos, REPORTS, Resistencia bacteriana.

Increasing Burden of Invasive Group B Streptococcal Disease in Nonpregnant Adults, 1990–2007 Clinical Practice Guidelines for the Diagnosis and Management of Intravascular Catheter-Related Infection: 2009 Update by the Infectious Diseases Society of America

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