Antitrypanosomal Therapy for Chronic Chagas’ Disease

June 30, 2011 at 6:33 pm Leave a comment

New Engl J of Med June 30, 2011

Clinical Therapeutics

Caryn Bern, M.D., M.P.H.

A 42-year-old woman presents to her physician with a letter stating that after she made a recent blood donation, a serologic test of her donated blood was positive for Chagas’ disease. The patient was born inEl Salvadorand moved to theUnited Stateswhen she was 18 years of age. Her three children are 8, 13, and 16 years of age. Her medical history is remarkable only for a cholecystectomy 2 years earlier; she reports no cardiac or gastrointestinal symptoms. Her physical examination is unremarkable. Electrocardiography (ECG) shows sinus rhythm at a rate of 72 beats per minute and a complete right bundle-branch block. An echocardiogram shows mild left ventricular segmental wall-motion abnormalities, but a normal ejection fraction and left ventricular diameter. The patient is referred to an infectious-disease consultant, who recommends antitrypanosomal therapy….

FULL TEXT

http://www.nejm.org/doi/full/10.1056/NEJMct1014204

PDF

http://www.nejm.org/doi/pdf/10.1056/NEJMct1014204

Entry filed under: Antiparasitarios, Epidemiología, Infecciones emergentes, Infecciones parasitarias, Medicina del viajero, Metodos diagnosticos.

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