Polyarthritis in four patients with chikungunya arthritis.

June 30, 2012 at 10:06 pm

Singapore Med J. 2012 Apr  V.53 N.4 P.241-3.

Lui NL, Leong HN, Thumboo J.

Department of Rheumatology and Immunology, Singapore General Hospital, Outram Road, Singapore 169608. lui.nai.lee@sgh.com.sg

Abstract

The incidence of chikungunya infection inSingaporehas been on the rise since the first reported case in 2006. Acute polyarthritis, a common manifestation among affected patients, may precede fever and present with debilitating arthritis to rheumatologists, orthopaedists, internists and primary care physicians. The diagnosis of chikungunya infection requires careful history taking and a high index of suspicion, with supporting evidence from the reverse transcription-polymerase chain reaction or the chikungunya IgM serology test. Treatment of chikungunya arthritis usually involves non-steroidal anti-inflammatory drugs. Rarely, polyarthritis in chikungunya may persist even after resolution of the acute infection, necessitating treatment with disease-modifying anti-rheumatic drugs. In this article, we present the different manifestations of chikungunya arthritis in our local setting and review the literature.

PDF

http://smj.sma.org.sg/5304/5304cs1.pdf

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Entry filed under: Biología Molecular, Infecciones virales, Medicina del viajero, Metodos diagnosticos, REVIEWS.

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