Archive for February 28, 2013

Medidas preventivas para el control de las enfermedades respiratorias y de transmisión aérea – 2010 128 págs.

Manual Separ de Procedimientos

Sociedad Española de Neumología y Cirugía Torácica (SEPAR)



Conceptos generales de prevención

Normas de aislamiento.

Medidas preventivas en los procedimientos diagnósticos y terapéuticos respiratorios.

Medidas preventivas de infecciones nosocomiales.

Medidas preventivas en situaciones específicas: Infecciones respiratorias víricas y gripe

Medidas preventivas en situaciones específicas: Tuberculosis

Medidas preventivas en situaciones específicas: Legionela

Medidas preventivas en situaciones específicas: Fibrosis Quística y Bronquiectasias

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February 28, 2013 at 2:45 pm

Treatment failure of pharyngeal gonorrhoea with internationally recommended first-line ceftriaxone verified in Slovenia, September 2011.

Euro Surveill. 2012 Jun 21;17(25).

Unemo M, Golparian D, Potočnik M, Jeverica S.


World Health Organization Collaborating Centre for Gonorrhoea and other Sexually Transmitted Infections, Swedish Reference Laboratory for Pathogenic Neisseria, Department of Laboratory Medicine, Microbiology, Örebro University Hospital, Örebro, Sweden.


We describe the second case in Europe of verified treatment failure of pharyngeal gonorrhoea, caused by an internationally occurring multidrug-resistant gonococcal clone, with recommended first-line ceftriaxone 250 mg in Slovenia. This is of grave concern since ceftriaxone is last remaining option for empirical treatment. Increased awareness of ceftriaxone failures, more frequent test-of-cure, strict adherence to regularly updated treatment guidelines, and thorough verification/falsification of suspected treatment failures are essential globally. New effective treatment options are imperative.


February 28, 2013 at 2:43 pm

The 2012 European guideline on the diagnosis and treatment of gonorrhoea in adults recommends dual antimicrobial therapy.

Euro Surveill. 2012 Nov 22;17(47).

Unemo M; European STI Guidelines Editorial Board.



February 28, 2013 at 2:41 pm

Tackling multidrug-resistant gonorrhea: how should we prepare for the untreatable?

Expert Rev Anti Infect Ther. 2012 Aug;10(8):831-3.

Kidd S, Kirkcaldy R, Weinstock H, Bolan G.


February 28, 2013 at 2:40 pm

Update to CDC’s Sexually transmitted diseases treatment guidelines, 2010: oral cephalosporins no longer a recommended treatment for gonococcal infections.

MMWR Morb Mortal Wkly Rep. 2012 Aug 10;61(31):590-4.

Centers for Disease Control and Prevention (CDC).


Gonorrhea is a major cause of serious reproductive complications in women and can facilitate human immunodeficiency virus (HIV) transmission. Effective treatment is a cornerstone of U.S. gonorrhea control efforts, but treatment of gonorrhea has been complicated by the ability of Neisseria gonorrhoeae to develop antimicrobial resistance. This report, using data from CDC’s Gonococcal Isolate Surveillance Project (GISP), describes laboratory evidence of declining cefixime susceptibility among urethral N. gonorrhoeae isolates collected in the United States during 2006-2011 and updates CDC’s current recommendations for treatment of gonorrhea. Based on GISP data, CDC recommends combination therapy with ceftriaxone 250 mg intramuscularly and either azithromycin 1 g orally as a single dose or doxycycline 100 mg orally twice daily for 7 days as the most reliably effective treatment for uncomplicated gonorrhea. CDC no longer recommends cefixime at any dose as a first-line regimen for treatment of gonococcal infections. If cefixime is used as an alternative agent, then the patient should return in 1 week for a test-of-cure at the site of infection.


PDF (see pag. 590)

February 28, 2013 at 2:39 pm


February 2013

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