Treatment failure of pharyngeal gonorrhoea with internationally recommended first-line ceftriaxone verified in Slovenia, September 2011.

February 28, 2013 at 2:43 pm

Euro Surveill. 2012 Jun 21;17(25).

Unemo M, Golparian D, Potočnik M, Jeverica S.

Source

World Health Organization Collaborating Centre for Gonorrhoea and other Sexually Transmitted Infections, Swedish Reference Laboratory for Pathogenic Neisseria, Department of Laboratory Medicine, Microbiology, Örebro University Hospital, Örebro, Sweden. magnus.unemo@orebroll.se

Abstract

We describe the second case in Europe of verified treatment failure of pharyngeal gonorrhoea, caused by an internationally occurring multidrug-resistant gonococcal clone, with recommended first-line ceftriaxone 250 mg in Slovenia. This is of grave concern since ceftriaxone is last remaining option for empirical treatment. Increased awareness of ceftriaxone failures, more frequent test-of-cure, strict adherence to regularly updated treatment guidelines, and thorough verification/falsification of suspected treatment failures are essential globally. New effective treatment options are imperative.

PDF

http://www.eurosurveillance.org/images/dynamic/EE/V17N25/art20200.pdf

Entry filed under: Antimicrobianos, Bacterias, Infecciones de transmision sexual, Infecciones oro-faríngeas, Metodos diagnosticos, REPORTS, Resistencia bacteriana.

The 2012 European guideline on the diagnosis and treatment of gonorrhoea in adults recommends dual antimicrobial therapy. Medidas preventivas para el control de las enfermedades respiratorias y de transmisión aérea – 2010 128 págs.


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