Archive for March 9, 2013

Sexually Transmitted Diseases (STDs) – Questions & Answers – 2010 Treatment Guidelines

The questions contained on this webpage were submitted by participants during the “2010 STD Treatment Guidelines Webinar: An Overview by CDC and the NNPTC” which aired on January 13, 2011.

The answers were composed by STD clinical experts in the National Network of STD/HIV Prevention Training Centers (NNPTC) and the CDC, edited by the webinar panel members (Gail Bolan, MD; Edward (Ned) Hook III, MD; and Jeanne Marrazzo, MD, MPH) and then reviewed and edited by Kimberly Workowski, MD, the lead author of the 2010 STD Treatment Guidelines, to ensure that the answers were aligned with the current STD Treatment Guidelines.

This webinar is the first in a series of STD Treatment Guidelines webinars produced by the CDC and the NNPTC following the release of the 2010 Treatment Guidelines in December, 2010.

More than 150 questions were submitted following a webinar on the 2010 STD Treatment Guidelines. The questions and their answers are now available, including answers on the following topics.

Click on a category below to view questions and answers:

Children and Adolescents

Chlamydia

Chlamydia/Gonorrhea Retesting

Expedited Partner Therapy

Genital Herpes

Gonorrhea

Human Papillomavirus (HPV)

Lymphogranuloma Venereum (LGV)

Miscellaneous

Mycoplasma genitalium

Pelvic Inflammatory Disease (PID)

Sexual Assault

STD Screening

Syphilis

Vaginitis

FULL TEXT

http://www.cdc.gov/std/treatment/2010/QandA/default.htm?s_CID=govd-std-009

March 9, 2013 at 11:57 am

“Ten Commandments” for the Appropriate use of Antibiotics by the Practicing Physician in an Outpatient Setting.

Front Microbiol. 2011;2:230.

Levy-Hara G, Amábile-Cuevas CF, Gould I, Hutchinson J, Abbo L, Saxynger L, Vlieghe E, Cardoso FL, Methar S, Kanj S, Ohmagari N, Harbarth S; International Society of Chemotherapy Antimicrobial Stewardship Working Group.

Source

Division of Infectious Diseases, Hospital Carlos Durand, University of Buenos Aires Buenos Aires, Argentina.

Abstract

A multi-national working group on antibiotic stewardship, from the International Society of Chemotherapy, put together ten recommendations to physicians prescribing antibiotics to outpatients. These recommendations are: (1) use antibiotics only when needed; teach the patient how to manage symptoms of non-bacterial infections;

(2) select the adequate ATB; precise targeting is better than shotgun therapy;

(3) consider pharmacokinetics and pharmacodynamics when selecting an ATB; use the shortest ATB course that has proven clinical efficacy;

(4) encourage patients’ compliance;

(5) use antibiotic combinations only in specific situations;

(6) avoid low quality and sub-standard drugs; prevent prescription changes at the drugstore;

(7) discourage self-prescription;

(8) follow only evidence-based guidelines; beware those sponsored by drug companies;

(9) rely (rationally) upon the clinical microbiology lab; and

(10) prescribe ATB empirically – but intelligently; know local susceptibility trends, and also surveillance limitations.

FULL TEXT

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225075/

PDF

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225075/pdf/fmicb-02-00230.pdf

March 9, 2013 at 11:54 am

Rapid detection of carbapenemase-producing Enterobacteriaceae.

Emerg Infect Dis. 2012 Sep;18(9):1503-7.

Nordmann P, Poirel L, Dortet L.

Source

Service de Bactériologie-Virologie, Hôpital de Bicêtre 78 Rue du Général Leclerc, 94275 K-Bicêtre, France. nordmann.patrice@bct.aphp.fr

Abstract

To rapidly identify carbapenemase producers in Enterobacteriaceae, we developed the Carba NP test. The test uses isolated bacterial colonies and is based on in vitro hydrolysis of a carbapenem, imipenem. It was 100% sensitive and specific compared with molecular-based techniques. This rapid (<2 hours), inexpensive technique may be implemented in any laboratory.

PDF

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437707/pdf/12-0355.pdf

March 9, 2013 at 11:52 am


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