Stillbirth During Infection With Middle East Respiratory Syndrome Coronavirus

December 20, 2014 at 3:24 pm

Journal of Infectious Diseases June 15, 2014 V.209 N.12 P.1870-1872


Daniel C. Payne1, Ibrahim Iblan6, Sultan Alqasrawi7, Mohannad Al Nsour9, Brian Rha1,2, Rania A. Tohme3, Glen R. Abedi1, Noha H. Farag4, Aktham Haddadin8, Tarek Al Sanhouri8, Najwa Jarour7, David L. Swerdlow1, Denise J. Jamieson5, Mark A. Pallansch1, Lia M. Haynes1, Susan I. Gerber1, Mohammad Mousa Al Abdallat7, for the Jordan MERS-CoV Investigation Teama

1Division of Viral Diseases, National Center for Immunization and Respiratory Diseases

2Epidemic Intelligence Service

3Global Immunization Division, Center for Global Health

4Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases

5Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia

6Jordan Field Epidemiology Training Program

7Communicable Diseases Directorate

8Directorate of Laboratories, Jordan Ministry of Health

9Eastern Mediterranean Public Health Network, Amman, Jordan

Correspondence: Daniel C. Payne, PhD, MSPH, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop A-34, Atlanta, GA 30333 (


We conducted an epidemiologic investigation among survivors of an outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in Jordan.

A second-trimester stillbirth occurred during the course of an acute respiratory illness that was attributed to MERS-CoV on the basis of exposure history and positive results of MERS-CoV serologic testing.

This is the first occurrence of stillbirth during an infection with MERS-CoV and may have bearing upon the surveillance and management of pregnant women in settings of unexplained respiratory illness potentially due to MERS-CoV.

Future prospective investigations of MERS-CoV should ascertain pregnancy status and obtain further pregnancy-related data, including biological specimens for confirmatory testing.


Entry filed under: Biología Molecular, Epidemiología, Infecciones emergentes, Infecciones en embarzadas, Infecciones respiratorias, Infecciones virales, Medicina del viajero, Metodos diagnosticos, REPORTS, Sepsis, Update. Tags: .

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