Risk factors for prosthetic joint infection – Case-control study (Article)
Clinical Infectious Diseases November 1998 V.27 N.5 P.1247-1254
Berbari, E.F.a, Hanssen, A.D.a, Duffy, M.C.a, Steckelberg, J.M.a, Ilstrup, D.M.a, Harmsen, W.S.a, Osmon, D.R.ab
a Division of Infectious Diseases, Department of Orthopedics, Mayo Clinic and Mayo Foundation, Rochester, MN, United States
b Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic/Mayo Foundation, 200 First Street Southwest, Rochester, MN 55905, United States
We conducted a matched case-control study to determine risk factors for the development of prosthetic joint infection. Cases were patients with prosthetic hip or knee joint infection.
Controls were patients who underwent total hip or knee arthroplasty and did not develop prosthetic joint infection.
A multiple logistic regression model indicated that risk factors for prosthetic joint infection were the development of a surgical site infection not involving the prosthesis (odds ratio [OR], 35.9; 95% confidence interval [CI], 8.3-154.6), a National Nosocomial Infections Surveillance (NNIS) System surgical patient risk index score of 1 (OR, 1.7; 95% CI, 1.2- 2.3) or 2 (OR, 3.9; 95% CI, 2.0-7.5), the presence of a malignancy (OR, 3.1; 95% CI, 1.3-7.2), and a history of joint arthroplasty (OR, 2.0; 95% CI, 1.4- 3.0).
Our findings suggest that a surgical site infection not involving the joint prosthesis, an NNIS System surgical patient risk index score of 1 or 2, the presence of a malignancy, and a history of a joint arthroplasty are associated with an increased risk of prosthetic joint infection.
Entry filed under: Antimicrobianos, Bacterias, Epidemiología, F.O.D, FIEBRE en el POSTOPERATORIO, Health Care-Associated Infections, Infecciones nosocomiales, Infecciones osteo-articulares-musculares, Infecciones relacionadas a prótesis, Metodos diagnosticos, REPORTS, Sepsis.