N Engl J of Medicine March.12, 2015 V.372 P.1048-1054
G.J. Wise and P.N. Schlege
From the Department of Urology, Weill Cornell Medical College, New York–Presbyterian Hospital, New York.
Address reprint requests to Dr. Wise at the Department of Urology, Weill Cornell Medical College, New York–Presbyterian Hospital, 525 E. 68th St., New York, NY 10065, or at firstname.lastname@example.org
Pyuria is defined as the presence of 10 or more white cells per cubic millimeter in a urine specimen, 3 or more white cells per high-power field of unspun urine, a positive result on Gram’s staining of an unspun urine specimen, or a urinary dipstick test that is positive for leukocyte esterase.1 Sterile pyuria is the persistent finding of white cells in the urine in the absence of bacteria, as determined by means of aerobic laboratory techniques (on a 5% sheep-blood agar plate and MacConkey agar plate)…….