Community-Acquired Pyelonephritis in Pregnancy Caused by KPC-Producing Klebsiella pneumoniae
Antimicrobial Agents and Chemotherapy AUG. 2015 V.59 N.8 P.4375-4378
Asma Khatri, Nina Naeger Murphy, Peter Wiest, Melissa Osborn, Kathleen Garber, Michelle Hecker, Kelly Hurless, Susan D. Rudin, Michael R. Jacobs, Robert C. Kalayjian, Robert A. Salata, David van Duin, Federico Perez, Robert A. Bonomo, David L. Paterson, and Patrick N. A. Harris
aMetroHealth Medical Center, Cleveland, Ohio, USA
bCase Western Reserve University, Cleveland, Ohio, USA
cUniversity of North Carolina, Chapel Hill, North Carolina, USA
dUniversity Hospitals Case Medical Center, Cleveland, Ohio, USA
eLouis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA
fUniversity of Queensland Centre for Clinical Research, Royal Brisbane and Women’s Hospital, Brisbane, Australia
Carbapenem-resistant Enterobacteriaceae (CRE) usually infect patients with significant comorbidities and health care exposures.
We present a case of a pregnant woman who developed community-acquired pyelonephritis caused by KPC-producing Klebsiella pneumoniae.
Despite antibiotic treatment, she experienced spontaneous prolonged rupture of membranes, with eventual delivery of a healthy infant.
This report demonstrates the challenge that CRE may pose to the effective treatment of common infections in obstetric patients, with potentially harmful consequences to maternal and neonatal health.