Bartonella spp. and Coxiella burnetii Associated with Community-Acquired, Culture-Negative Endocarditis, Brazil
Emerging Infectious Diseases Aug 2015 V.21 N.8
Rinaldo Focaccia Siciliano, Jussara Bianchi Castelli, Alfredo Jose Mansur, Fabiana Pereira dos Santos, Silvia Colombo, Elvira Mendes do Nascimento, Christopher D. Paddock, Roosecelis Araújo Brasil, Paulo Eduardo Neves Ferreira Velho, Marina Rovani Drummond, Max Grinberg, and Tania Mara Varejao Strabelli
University of São Paulo Medical School, São Paulo, Brazil (R.F. Siciliano, J.B. Castelli, A.J. Mansur, M. Grinberg, T.M.V. Strabelli); Adolfo Lutz Institute, São Paulo (F. Pereira dos Santos, S. Colombo, E.M. Nascimento, R.A. Brasil); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (C.D. Paddock); State University of Campinas Medical School, Campinas, Brazil (P.E.N.F. Velho, M.R. Drummond)
We evaluated culture-negative, community-acquired endocarditis by using indirect immunofluorescent assays and molecular analyses for Bartonella spp. and Coxiella burnetii and found a prevalence of 19.6% and 7.8%, respectively.
Our findings reinforce the need to study these organisms in patients with culture-negative, community-acquired endocarditis, especially B. henselae in cat owners.