KPC and NDM-1 Genes in Related Enterobacteriaceae Strains and Plasmids from Pakistan and the United States

August 28, 2015 at 8:21 am

Emerging Infectious Diseases Jun 2015 V.21 N.6

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Mitchell W. Pesesky1, Tahir Hussain1, Meghan Wallace, Bin Wang, Saadia Andleeb, Carey-Ann D. Burnham, and Gautam Dantas

Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA (M.W. Pesesky, T. Hussain. M. Wallace, B. Wang, C.D. Burnham, G. Dantas); National University of Sciences and Technology, Islamabad, Pakistan (T. Hussain, S. Andleeb)

To characterize the genomic context of New Delhi metallo-β-lactamase-1 (NDM-1) and Klebsiella pneumoniae carbapenemase (KPC), we sequenced 78 Enterobacteriaceae isolates from Pakistan and the United States encoding KPC, NDM-1, or no carbapenemase.

High similarities of the results indicate rapid spread of carbapenem resistance between strains, including globally disseminated pathogens.

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http://wwwnc.cdc.gov/eid/article/21/6/pdfs/14-1504.pdf

Entry filed under: Antimicrobianos, Bacterias, Bacteriemias, Biología Molecular, Epidemiología, Infecciones emergentes, Metodos diagnosticos, Resistencia bacteriana, Sepsis, Update. Tags: .

Extensively Drug-Resistant New Delhi Metallo-β-Lactamase–Encoding Bacteria in the Environment, Dhaka, Bangladesh, 2012 Mycoplasma pneumoniae and Chlamydia spp. Infection in Community-Acquired Pneumonia, Germany, 2011–2012


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