Successful Treatment of Carbapenemase-Producing Pandrug-Resistant Klebsiella pneumoniae Bacteremia

September 18, 2015 at 8:15 pm

Antimicrobial Agents and Chemotherapy OCT 2015 V.59 N.10 P.5903-5908

Jose F. Camargo, Jacques Simkins, Thiago Beduschi, Akin Tekin, Laura Aragon, Armando Pérez-Cardona, Clara E. Prado, Michele I. Morris, Lilian M. Abbo, and Rafael Cantón

aDepartment of Medicine, Division of Infectious Diseases, University of Miami Miller School of Medicine, Miami, Florida, USA

bMiami Transplant Institute and Department of Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA

cDepartment of Pharmacy, Jackson Memorial Hospital, Miami, Florida, USA

dDepartment of Microbiology, Jackson Memorial Hospital, Miami, Florida, USA

eDepartment of Microbiology, University of Miami, Miami, Florida, USA

fServicio de Microbiología, Hospital Universitario Ramón y Cajal and Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain

gRed Española de Investigación en Patología Infecciosa (REIPI), Madrid, Spain

New antibiotic options are urgently needed for the treatment of carbapenem-resistant Enterobacteriaceae infections.

We report a 64-year-old female with prolonged hospitalization following an intestinal transplant who developed refractory bacteremia due to a serine carbapenemase-producing pandrug-resistant isolate of Klebsiella pneumoniae.

After failing multiple antimicrobial regimens, the patient was successfully treated.

abstract

http://aac.asm.org/content/59/10/5903.abstract?etoc

PDF

http://aac.asm.org/content/59/10/5903.full.pdf

 

Entry filed under: Antimicrobianos, Bacterias, Bacteriemias, Metodos diagnosticos, REPORTS, Resistencia bacteriana, Sepsis, Update. Tags: .

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