Prosthetic Joint Infection

September 19, 2015 at 9:41 am

Clinical Microbiology Reviews APR 2014 V.27 N.2 P.302-345

Aaron J. Tande and Robin Patel

aDivision of Infectious Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA

bDivision of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA

Prosthetic joint infection (PJI) is a tremendous burden for individual patients as well as the global health care industry.

While a small minority of joint arthroplasties will become infected, appropriate recognition and management are critical to preserve or restore adequate function and prevent excess morbidity.

In this review, we describe the reported risk factors for and clinical manifestations of PJI. We discuss the pathogenesis of PJI and the numerous microorganisms that can cause this devastating infection.

The recently proposed consensus definitions of PJI and approaches to accurate diagnosis are reviewed in detail. An overview of the treatment and prevention of this challenging condition is provided.

abstract

http://cmr.asm.org/content/27/2/302.abstract

PDF

http://cmr.asm.org/content/27/2/302.full.pdf

Entry filed under: Antimicrobianos, Bacterias, Biología Molecular, Epidemiología, Health Care-Associated Infections, Infecciones nosocomiales, Infecciones osteo-articulares-musculares, Infecciones relacionadas a prótesis, Metodos diagnosticos, Resistencia bacteriana, REVIEWS, Sepsis, Update. Tags: .

Disease Manifestations and Pathogenic Mechanisms of Group A Streptococcus Propionibacterium acnes: from Commensal to Opportunistic Biofilm-Associated Implant Pathogen


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