Successful Treatment of Carbapenemase-Producing Pandrug-Resistant Klebsiella pneumoniae Bacteremia.

October 5, 2015 at 2:52 pm

Antimicrob Agents Chemother. 2015 Oct;59(10):5903-8.

Camargo JF1, Simkins J2, Beduschi T3, Tekin A3, Aragon L4, Pérez-Cardona A5, Prado CE6, Morris MI2, Abbo LM2, Cantón R7.

Author information

1Department of Medicine, Division of Infectious Diseases, University of Miami Miller School of Medicine, Miami, Florida, USA jfc31@med.miami.edu rafael.canton@salud.madrid.org

2Department of Medicine, Division of Infectious Diseases, University of Miami Miller School of Medicine, Miami, Florida, USA.

3Miami Transplant Institute and Department of Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.

4Department of Pharmacy, Jackson Memorial Hospital, Miami, Florida, USA.

5Department of Microbiology, Jackson Memorial Hospital, Miami, Florida, USA.

6Department of Microbiology, University of Miami, Miami, Florida, USA.

7Servicio de Microbiología, Hospital Universitario Ramón y Cajal and Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain Red Española de Investigación en Patología Infecciosa (REIPI), Madrid, Spain jfc31@med.miami.edu rafael.canton@salud.madrid.org

Abstract

New antibiotic options are urgently needed for the treatment of carbapenem-resistant Enterobacteriaceae infections.

We report a 64-year-old female with prolonged hospitalization following an intestinal transplant who developed refractory bacteremia due to a serine carbapenemase-producing pandrug-resistant isolate of Klebsiella pneumoniae.

After failing multiple antimicrobial regimens, the patient was successfully treated.

PDF

http://aac.asm.org/content/59/10/5903.full.pdf

Entry filed under: Antimicrobianos, Bacterias, Bacteriemias, Biología Molecular, Epidemiología, Health Care-Associated Infections, HIC no SIDA, Infecciones emergentes, Infecciones en transplantados, Infecciones nosocomiales, Metodos diagnosticos, REPORTS, Resistencia bacteriana, Sepsis, Update. Tags: .

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