J Community Hosp Intern Med Perspect. 2012 Jan 26;1(4).
Tabacco J1, Suniega E, Sarabchi F, Mitsani D.
1Union Memorial Hospital, Baltimore, MD, USA.
Within the past six years, a case of both Waterhouse-Freidrichsen Syndrome and fulminant meningococcemia have presented to Union Memorial Hospital.
Both cases presented in markedly different fashions, differed in microbiologic serogrouping, showed minimal histopathologic similarities; however achieved ultimately the same outcome through two different pathological pathways.
The following case reports illustrate two mechanisms through which N. Meningitis may pathogenize a host, both leading to complete cardiovascular collapse in less than 12 hours.