Ceftaroline fosamil: A super-cephalosporin?

October 26, 2015 at 9:41 pm

Cleve Clin J Med. 2015 Jul;82(7):437-44.

Ghamrawi RJ1, Neuner E2, Rehm SJ3,4.

Author information

1Clinical Pharmacist Specialist, Adult Antimicrobial Stewardship Department of Pharmacy, University Hospitals Case Medical Center, Cleveland, OH, USA.

2Infectious Diseases Clinical Specialist, Department of Pharmacy, Cleveland Clinic, Cleveland, OH, USA. E-mail: neunere@ccf.org

3Department of Infectious Disease, Cleveland Clinic, Cleveland, OH, USA.

4Clinical Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.

Abstract

Ceftaroline is a broad-spectrum cephalosporin used to treat infections caused by a variety of microorganisms, including methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Streptococcus pneumoniae.

However, it is not active against Pseudomonas aeruginosa, Bacteroides fragilis, and carbapenem-resistant Enterobacteriaceae.

Its approved indications include community-acquired bacterial pneumonia and bacterial infections of skin and skin structures.

It has also been used off-label to treat osteomyelitis, endocarditis, and meningitis caused by ceftaroline-susceptible organisms.

PDF

http://www.ccjm.org/view-pdf.html?file=uploads/media/Ghamrawi_CeftarolineFosamil

Entry filed under: Antimicrobianos, Bacterias, Bacteriemias, Infecciones cardio-vasculares, Infecciones del SNC, Infecciones en piel y tej blandos, Infecciones osteo-articulares-musculares, Infecciones respiratorias, Metodos diagnosticos, Resistencia bacteriana, Sepsis, Update. Tags: .

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