Effectiveness of Meningococcal B Vaccine against Endemic Hypervirulent Neisseria meningitidis W Strain, England
EID FEB 2016 V.22 N.2
Shamez N. Ladhani, Marzia Monica Giuliani, Alessia Biolchi, Mariagrazia Pizza, Kazim Beebeejaun, Jay Lucidarme, Jamie Findlow, Mary E. Ramsay, and Ray Borrow
St. George’s University of London Paediatric Infectious Diseases Research Group, London, UK (S.N. Ladhani); Public Health England, London (S.N. Ladhani, K. Beebeejaun, M.E. Ramsay); GSK Vaccines, Siena, Italy (M.M. Giuliani, A. Biolchi, M. Pizza); Public Health England, Manchester, UK (J. Lucidarme, J. Findlow, R. Borrow)
Serum samples from children immunized with a meningococcal serogroup B vaccine demonstrated potent serum bactericidal antibody activity against the hypervirulent Neisseria meningitidis serogroup W strain circulating in England.
The recent introduction of this vaccine into the United Kingdom national immunization program should also help protect infants against this endemic strain.