High Prevalence of vanM in Vancomycin-Resistant Enterococcus faecium Isolates from Shanghai, China
Antimicrobial Agents and Chemotherapy December 2015 V.59 N.12 P.7795-7798
Chunhui Chen, Jingyong Sun, Yan Guo, Dongfang Lin, Qinglan Guo, Fupin Hu, Demei Zhu, Xiaogang Xu, and Minggui Wang
aInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China
bKey Laboratory of Clinical Pharmacology of Antibiotics, Ministry of Health, Shanghai, China
cDepartment of Clinical Microbiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
The vanM gene was first found in a vancomycin-resistant Enterococcus faecium (VREm) isolate in Shanghai in 2006.
In this study, we found that, in 70 VREm strains isolated in nine Shanghai hospitals from 2006 to 2014, vanM was more prevalent than the vanA gene (64.3% [45/70] versus 35.7% [25/70]).
The vanM-type isolates showed similar antimicrobial susceptibility patterns with the vanA types. The vanM-type VREm emerged and disseminated in Shanghai.