Role of Serologic and Molecular Diagnostic Assays in Identification and Management of Hepatitis C Virus Infection
Journal of Clinical Microbiology February 2016 V.54 N.2 P.265-273
Gavin Cloherty, Andrew Talal, Kelly Coller, Corklin Steinhart, John Hackett Jr., George Dawson, Juergen Rockstroh, and Jordan Feld
aAbbott Diagnostics, Abbott Park, Illinois, USA
bUniversity at Buffalo, Buffalo, New York, USA
cViiV Healthcare, Research Triangle Park, North Carolina, USA
dUniversity Bonn, Bonn, Germany
eUniversity of Toronto, Toronto, Canada
The drugs available for the treatment of hepatitis C virus (HCV) have evolved to provide shorter treatment duration and higher rates of sustained virologic response (SVR), and the role of HCV infection diagnostic tests has had to evolve in order to meet changing clinical needs.
This review gives an overview on the role of HCV infection diagnostic testing (molecular and serological tools) used in the diagnosis and management of HCV infection.
All of this critical information guides physician decisions to optimize patient clinical outcomes. Also discussed is the future direction of diagnostic testing in the context of further advances in drug development.
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