Indirect resistance to several classes of antibiotics in cocultures with resistant bacteria expressing antibiotic-modifying or -degrading enzymes
Journal of Antimicrobial and Chemotherapy January 2016 V.71 N.1 P.100-110
Hervé Nicoloff and Dan I. Andersson
Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden
The detection of indirect resistance in vitro suggests that coinfecting bacteria from the normal microbial flora may have a more important negative impact during antimicrobial therapy than is generally appreciated.