Postpandemic Influenza A/H1N1pdm09 is still Causing Severe Perinatal Complications.
Mediterr J Hematol Infect Dis. 2015 Jan 1;7(1):e2015007.
Bogers H1, Bos D1, Schoenmakers S1, Duvekot JJ1.
1Erasmus MC, University Medical Centre Rotterdam, Department of Obstetrics and Gynaecology, Division of Obstetrics and Prenatal Medicine, University Medical Centre Rotterdam.
Although influenza A/H1N1pdm09 is not causing a pandemic anymore, we recently observed two critically ill pregnant women infected by this virus.
We present these cases to illustrate the possible severe complications of an – at that moment – seasonal influenza in pregnancy.
We discuss the epidemiological differences between the pandemic and post pandemic phase and try to explain the high virulence of influenza A/H1N1pdm09 -infections in pregnancy by discussing insights in immunology during pregnancy.
We conclude that although influenza A/H1N1pdm09 is in the post pandemic phase, infection by this influenza virus still needs to be considered in pregnant women with progressive respiratory dysfunction.