Possible Airborne Person-to-Person Transmission of Mycobacterium bovis — Nebraska 2014–2015

March 4, 2016 at 11:54 am

MMWR Morb Mortal Wkly Rep 2016;65:197–201

Bryan F. Buss, DVM; Alison Keyser-Metobo, MPH; Julie Rother; et al.

Mycobacterium bovis, one of several mycobacteria of the M. tuberculosis complex, is a global zoonotic pathogen that primarily infects cattle. Humans become infected by consuming unpasteurized dairy products from infected cows (1,2); possible person-to-person airborne transmission has also been reported (3). In April 2014, a man in Nebraska who was born in Mexico was determined to have extensive pulmonary tuberculosis (TB) caused by M. bovis after experiencing approximately 3 months of cough and fever. Four months later, a U.S.-born Hispanic girl from a nearby town who had been ill for 4–5 months was also determined to have pulmonary TB caused by M. bovis. The only social connection between the two patients was attendance at the same church, and no common dietary exposure was identified. Both patients had pulmonary cavities on radiography and acid-fast bacilli (AFB) on sputum-smear microscopy, indicators of being contagious (4). Whole-genome sequencing results of the isolates were nearly indistinguishable. Initial examination of 181 contacts determined that 39 (22%) had latent infection: 10 (42%) of 24 who had close exposure to either patient, 28 (28%) of 100 who were exposed to one or both patients in church, and one (2%) of 57 exposed to the second patient at a school……

PDF

http://www.cdc.gov/mmwr/volumes/65/wr/pdfs/mm6508a1.pdf

Entry filed under: Biología Molecular, Epidemiología, Infecciones emergentes, Infecciones respiratorias, Metodos diagnosticos, Micobacterias, REPORTS, Sepsis, Update, Zoonosis. Tags: .

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