Zika Virus

April 21, 2016 at 3:24 pm

N Engl J Med April 21, 2016 V.374 P.1552-1563

REVIEW ARTICLE

L.R. Petersen, D.J. Jamieson, A.M. Powers, and M.A. Honein

From the Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO (L.R.P., A.M.P.); and the Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion (D.J.J), and the Division of Congenital and Developmental Disorders, National Center on Birth Defects and Developmental Disabilities (M.A.H), Centers for Disease Control and Prevention, Atlanta.

In 1947, a study of yellow fever yielded the first isolation of a new virus, from the blood of a sentinel rhesus macaque that had been placed in the Zika Forest of Uganda.1 Zika virus remained in relative obscurity for nearly 70 years; then, within the span of just 1 year, Zika virus was introduced into Brazil from the Pacific Islands and spread rapidly throughout the Americas.2 It became the first major infectious disease linked to human birth defects to be discovered in more than half a century and created such global alarm that the World Health Organization (WHO) would declare a Public Health Emergency of International Concern.3 This review describes the current understanding of the epidemiology, transmission, clinical characteristics, and diagnosis of Zika virus infection, as well as the future outlook with regard to this disease…

PDF

http://www.nejm.org/doi/pdf/10.1056/NEJMra1602113

Entry filed under: Biología Molecular, Epidemiología, FIEBRE en el POST-VIAJE, FIEBRE y RASH, Infecciones de transmision sexual, Infecciones del SNC, Infecciones emergentes, Infecciones en embarzadas, Infecciones virales, Medicina del viajero, Metodos diagnosticos, Update, Zoonosis. Tags: .

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