Fungal periprosthetic joint infection of the hip: a systematic review.

July 4, 2016 at 9:04 am

Orthop Rev (Pavia). 2015 Mar 31;7(1):5748.

Schoof B1, Jakobs O1, Schmidl S1, Klatte TO2, Frommelt L3, Gehrke T1, Gebauer M1.

Author information

1Department of Orthopedic Surgery, HELIOS Endo-Clinic Hamburg , Hamburg, Germany.

2Department of Trauma-, Hand- and Reconstructive Surgery, University Medical Center Hamburg-Eppendorf , Hamburg, Germany.

3Centre of Infections and Microbiology, HELIOS Endo-Clinic , Hamburg, Germany.


Periprosthetic joint infection (PJI) is a severe complication of total joint arthroplasty with an incidence of approximately 1%. Due to the high risk of persisting infection, successful treatment of fungal PJI is challenging. The purpose of this study was to gain insight into the current management of fungal PJI of the hip and, by systematically reviewing the cases published so far, to further improve the medical treatment of this serious complication of total hip arthroplasty. Thus, we conducted a systematic review of the available literature concerning fungal PJI in total hip arthroplasty, including 45 cases of fungal PJI. At the moment a two-stage revision procedure is favorable and there is an ongoing discussion on the therapeutic effect of antifungal drug loaded cement spacers on fungal periprosthetic infections of the hip. Due to the fact that there is rare experience with it, there is urgent need to establish guidelines for the treatment of fungal infections of total hip arthroplasty.



Entry filed under: Antimicoticos, Biología Molecular, CONSENSOS, Epidemiología, F.O.D, FIEBRE en el POSTOPERATORIO, GUIDELINES, Health Care-Associated Infections, Infecciones micoticas, Infecciones osteo-articulares-musculares, Infecciones relacionadas a prótesis, Metodos diagnosticos, REVIEWS, Sepsis, Update.

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