Brucellosis and the Respiratory System
Clin Infect Dis. (2003) 37 (7): e95-e99
Georgios Pappas, Mile Bosilkovski, Nikolaos Akritidis, Maria Mastora, Liliana Krteva, and Epaminondas Tsianos
1Department of Internal Medicine, University Hospital of Ioannina, Greece
2Department of Internal Medicine, Peripheral General Hospital “G. Hatzikosta,” Ioannina, Greece
3Clinic for Infectious Diseases and Febrile Conditions, Medical Faculty, Skopje, Former Yugoslav Republic of Macedonia
Brucellosis is a zoonotic disease that remains endemic worldwide. Its clinical manifestations and focal complications are often troublesome in making a diagnosis. Involvement of the respiratory system in brucellosis is an acknowledged but rare event that is only occasionally described in literature. We describe 37 cases of respiratory involvement during the course of brucellosis that presented as pneumonia, bronchopneumonia, pleural effusion with a predominance of monocytic or lymphocytic infiltrates, and paroxysmal dry cough. We also discuss aspects of the respiratory pathology, radiological characteristics, coexisting complications, and aspects of treatment of respiratory brucellosis.