Antiretrovirals for HIV Treatment and Prevention: The Challenges of Success

July 17, 2016 at 4:25 pm

JAMA July 12, 2016 V.316 N.2 P.151-153

Editorial

Kenneth H. Mayer, MD; Douglas S. Krakower, MD

1The Fenway Institute, Fenway Health, Boston, Massachusetts

2Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts

3Department of Medicine, Harvard Medical School, Boston, Massachusetts

After the first case reports of AIDS were described in 1981, it soon became clear that the epidemic constituted a public health emergency. Although the first antiretrovirals were evaluated in clinical trials in the 1980s, it was not until the mid-1990s that the clinical efficacy of combination antiretroviral chemotherapy was demonstrated to prevent immunocompromise and to restore health to people living with AIDS. When the International Antiviral Society–USA (IAS-USA) published its first antiretroviral guidelines in JAMA in conjunction with the International AIDS Conference in Vancouver in 1996,1 it represented the beginning of a new era, suggesting that the pandemic might be controlled by treatment. In the current issue of JAMA, the IAS-USA presents its most recent set of guidelines,2 reflecting substantial changes over the past 20 years in the development of more potent combinations of drugs with fewer adverse effects, the advent of coformulated medications, and the evidence that antiretroviral agents have a vital role in HIV prevention…..

FULL TEXT

http://jama.jamanetwork.com/article.aspx?articleid=2533044

Entry filed under: Antirretrovirales, HIV/SIDA, HIV/SIDA HAART, HIV/SIDA Prevencion. Tags: .

Condomless Sex With Virologically Suppressed HIV-Infected Individuals: How Safe Is It? Visions for an AIDS-Free Generation: Red Ribbons of Hope


Calendar

July 2016
M T W T F S S
« Jun   Aug »
 123
45678910
11121314151617
18192021222324
25262728293031

Most Recent Posts


%d bloggers like this: