Archive for August 4, 2016

Treatment Modalities and Antimicrobial Stewardship Initiatives in the Management of Intra-Abdominal Infections.

Antibiotics (Basel). 2016 Feb 15;5(1).

Hoffmann C1,2, Zak M3, Avery L4,5, Brown J6,7,8.

Author information

1Wegmans School of Pharmacy, St. John Fisher College, Rochester, NY 14618, USA. choffmann@sjfc.edu.

2Department of Pharmacy, University of Rochester Medical Center, Rochester, NY 14642, USA. choffmann@sjfc.edu.

3Wegmans School of Pharmacy, St. John Fisher College, Rochester, NY 14618, USA. mzak@sjfc.edu.

4Wegmans School of Pharmacy, St. John Fisher College, Rochester, NY 14618, USA. lavery@sjfc.edu.

5St. Joseph’s Hospital Health Center, Syracuse, NY 13203, USA. lavery@sjfc.edu.

6Wegmans School of Pharmacy, St. John Fisher College, Rochester, NY 14618, USA. jbrown@sjfc.edu.

7Department of Pharmacy, University of Rochester Medical Center, Rochester, NY 14642, USA. jbrown@sjfc.edu.

8Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA. jbrown@sjfc.edu.

Abstract

Antimicrobial stewardship programs (ASPs) focus on improving the utilization of broad spectrum antibiotics to decrease the incidence of multidrug-resistant Gram positive and Gram negative pathogens.

Hospital admission for both medical and surgical intra-abdominal infections (IAIs) commonly results in the empiric use of broad spectrum antibiotics such as fluoroquinolones, beta-lactam beta-lactamase inhibitors, and carbapenems that can select for resistant organisms.

This review will discuss the management of uncomplicated and complicated IAIs as well as highlight stewardship initiatives focusing on the proper use of broad spectrum antibiotics

abstract

http://www.mdpi.com/2079-6382/5/1/11

PDF (CLIC in DOWNLOAD PDF)

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August 4, 2016 at 9:28 am

Practice Guidelines for the Diagnosis and Management of Aspergillosis – 2016 Update by the Infectious Diseases Society of America

Clin Infect Dis. (2016) 63 (4): e1-e60

Thomas F. Patterson, George R. Thompson III, David W. Denning, Jay A. Fishman, Susan Hadley, Raoul Herbrecht, Dimitrios P. Kontoyiannis, Kieren A. Marr, Vicki A. Morrison, M. Hong Nguyen, Brahm H. Segal, William J. Steinbach, David A. Stevens, Thomas J. Walsh, John R. Wingard, Jo-Anne H. Young, and John E. Bennett

1University of Texas Health Science Center at San Antonio and South Texas Veterans Health Care System

2University of California, Davis

3National Aspergillosis Centre, University Hospital of South Manchester, University of Manchester, United Kingdom

4Massachusetts General Hospital and Harvard Medical School

5Tufts Medical Center, Boston, Massachusetts

6University of Strasbourg, France

7University of Texas MD Anderson Cancer Center, Houston

8Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland

9Hennepin County Medical Center and University of Minnesota, Minneapolis

10University of Pittsburgh, Pennsylvania

11University at Buffalo Jacobs School of Medicine and Biomedical Sciences, and Roswell Park Cancer Institute, New York

12Duke University Medical Center, Durham, North Carolina

13California Institute for Medical Research, San Jose

14New York–Presbyterian Hospital/Weill Cornell Medical Center, New York

15University of Florida, Gainesville

16University of Minnesota, Minneapolis

17Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland

It is important to realize that guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment with respect to particular patients or special clinical situations. IDSA considers adherence to these guidelines to be voluntary, with the ultimate determination regarding their application to be made by the physician in the light of each patient’s individual circumstances.

abstract

http://cid.oxfordjournals.org/content/63/4/433.abstract?sid=2377ea3f-a5d8-486b-aec1-5549df830d26

PDF

http://cid.oxfordjournals.org/content/63/4/433.full.pdf+html

August 4, 2016 at 9:24 am

Executive Summary: Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America

Clin Infect Dis. (2016) 63 (4): 433-442

Thomas F. Patterson, George R. Thompson III, David W. Denning, Jay A. Fishman, Susan Hadley, Raoul Herbrecht, Dimitrios P. Kontoyiannis, Kieren A. Marr, Vicki A. Morrison, M. Hong Nguyen, Brahm H. Segal, William J. Steinbach, David A. Stevens, Thomas J. Walsh, John R. Wingard, Jo-Anne H. Young, and John E. Bennett

1University of Texas Health Science Center at San Antonio and South Texas Veterans Health Care System

2University of California, Davis

3National Aspergillosis Centre, University Hospital of South Manchester, University of Manchester, United Kingdom

4Massachusetts General Hospital and Harvard Medical School

5Tufts Medical Center, Boston, Massachusetts

6University of Strasbourg, France

7University of Texas MD Anderson Cancer Center, Houston

8Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland

9Hennepin County Medical Center and University of Minnesota, Minneapolis

10University of Pittsburgh, Pennsylvania

11University at Buffalo Jacobs School of Medicine and Biomedical Sciences, and Roswell Park Cancer Institute, New York

12Duke University Medical Center, Durham, North Carolina

13California Institute for Medical Research, San Jose

14New York–Presbyterian Hospital/Weill Cornell Medical Center, New York

15University of Florida, Gainesville

16University of Minnesota, Minneapolis

17Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland

It is important to realize that guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment with respect to particular patients or special clinical situations. IDSA considers adherence to these guidelines to be voluntary, with the ultimate determination regarding their application to be made by the physician in the light of each patient’s individual circumstances.

abstract

http://cid.oxfordjournals.org/content/63/4/e1.abstract?sid=2377ea3f-a5d8-486b-aec1-5549df830d26

PDF

http://cid.oxfordjournals.org/content/63/4/e1.full.pdf+html

August 4, 2016 at 9:22 am


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