Listeria monocytogenes meningitis in an immunocompromised patient.
New Microbiol. 2015 Jan;38(1):113-8.
Barocci S1, Mancini A, Canovari B, Petrelli E, Sbriscia-Fioretti E, Licci A, D’Addesa S, Petrini G, Giacomini M, Renzi A, Migali A, Briscolini S.
1ASUR Marche AV2, O.U. Clinical Pathology, Senigallia (AN), Italy.
This report describes a case of meningitis caused by Listeria monocytogenes in a stem cell transplant recipient on immunosuppressive therapy for cutaneous chronic graft-versus host disease.
A 59-year-old woman had undergone allogeneic stem cell transplantation (from a matched unrelated donor) 13 months previously for chronic lymphocytic leukemia. She was on regular hematologic follow-up.
Though her previous malignancy has been in remission, she was immunosuppressed due to the pharmacological treatment.
We describe a meningitis caused by a typical food-borne pathogen, dangerous in patients with impaired cell-mediated immunity. Moreover the bacterium had a multidrug resistance, a rare characteristic in clinical listeriosis.
Rapid diagnosis and treatment are key factors in these cases. We chose ampicillin and rifampicin that allowed a complete resolution of the clinical manifestations.
Entry filed under: Antimicrobianos, Bacterias, Bacteriemias, Epidemiología, F.O.D, HIC no SIDA, Infecciones del SNC, Infecciones en onco-hematologicos, Infecciones en transplantados, Infecciones y Alimentos, Metodos diagnosticos, REPORTS, Resistencia bacteriana, Sepsis, Update, Zoonosis.