Listeria monocytogenes meningitis in an immunocompromised patient.

December 18, 2016 at 12:22 pm

New Microbiol. 2015 Jan;38(1):113-8.

Barocci S1, Mancini A, Canovari B, Petrelli E, Sbriscia-Fioretti E, Licci A, D’Addesa S, Petrini G, Giacomini M, Renzi A, Migali A, Briscolini S.

Author information

1ASUR Marche AV2, O.U. Clinical Pathology, Senigallia (AN), Italy.

Abstract

This report describes a case of meningitis caused by Listeria monocytogenes in a stem cell transplant recipient on immunosuppressive therapy for cutaneous chronic graft-versus host disease.

A 59-year-old woman had undergone allogeneic stem cell transplantation (from a matched unrelated donor) 13 months previously for chronic lymphocytic leukemia. She was on regular hematologic follow-up.

Though her previous malignancy has been in remission, she was immunosuppressed due to the pharmacological treatment.

We describe a meningitis caused by a typical food-borne pathogen, dangerous in patients with impaired cell-mediated immunity. Moreover the bacterium had a multidrug resistance, a rare characteristic in clinical listeriosis.

Rapid diagnosis and treatment are key factors in these cases. We chose ampicillin and rifampicin that allowed a complete resolution of the clinical manifestations.

PDF

http://www.newmicrobiologica.org/PUB/allegati_pdf/2015/1/113.pdf

Entry filed under: Antimicrobianos, Bacterias, Bacteriemias, Epidemiología, F.O.D, HIC no SIDA, Infecciones del SNC, Infecciones en onco-hematologicos, Infecciones en transplantados, Infecciones y Alimentos, Metodos diagnosticos, REPORTS, Resistencia bacteriana, Sepsis, Update, Zoonosis. Tags: .

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