First human case of fatal Halicephalobus gingivalis meningoencephalitis in Australia.

December 26, 2016 at 1:25 pm

J Clin Microbiol. 2015 May;53(5):1768-74.

Lim CK1, Crawford A2, Moore CV3, Gasser RB4, Nelson R5, Koehler AV4, Bradbury RS6, Speare R7, Dhatrak D2, Weldhagen GF3.

Author information

1Department of Microbiology, SA Pathology, Adelaide, South Australia, Australia The University of Adelaide, Adelaide, South Australia, Australia chuankok.lim@health.sa.gov.au

2Department of Histopathology, SA Pathology, Adelaide, South Australia, Australia.

3Department of Microbiology, SA Pathology, Adelaide, South Australia, Australia.

4Faculty of Veterinary Science, The University of Melbourne, Victoria, Australia.

5Royal Adelaide Hospital, Adelaide, South Australia, Australia.

6School of Medical and Applied Sciences, Central Queensland University, Rockhampton, Queensland, Australia.

7College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Queensland, Australia Tropical Health Solutions, Townsville, Queensland, Australia.

Abstract

Halicephalobus gingivalis (previously Micronema deletrix) is a free-living nematode known to cause opportunistic infections, mainly in horses.

Human infections are very rare, but all cases described to date involved fatal meningoencephalitis. Here we report the first case of H. gingivalis infection in an Australian human patient, confirmed by nematode morphology and sequencing of ribosomal DNA.

The implications of this case are discussed, particularly, the need to evaluate real-time PCR as a diagnostic tool.

PDF

http://jcm.asm.org/content/53/5/1768.full.pdf+html

Entry filed under: Antiparasitarios, Biología Molecular, Epidemiología, F.O.D, Infecciones del SNC, Infecciones emergentes, Infecciones parasitarias, Metodos diagnosticos, REVIEWS, Sepsis, Update, Zoonosis. Tags: .

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