Primary amoebic meningoencephalitis caused by Naegleria fowleri: an old enemy presenting new challenges.

February 13, 2017 at 8:47 am

PLoS Negl Trop Dis. 2014 Aug 14;8(8):e3017. doi: 10.1371/journal.pntd.0003017. eCollection 2014.

Siddiqui R1, Khan NA1.

Author information

1Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan.

Abstract

First discovered in 1899, Naegleria fowleri is a protist pathogen, known to infect the central nervous system and produce primary amoebic meningoencephalitis. The most distressing aspect is that the fatality rate has remained more than 95%, despite our advances in antimicrobial chemotherapy and supportive care. Although rare worldwide, most cases have been reported in the United States, Australia, and Europe (France). A large number of cases in developing countries go unnoticed. In particular, religious, recreational, and cultural practices such as ritual ablution and/or purifications, Ayurveda, and the use of neti pots for nasal irrigation can contribute to this devastating infection. With increasing water scarcity and public reliance on water storage, here we debate the need for increased awareness of primary amoebic meningoencephalitis and the associated risk factors, particularly in developing countries

PDF

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133175/pdf/pntd.0003017.pdf

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Entry filed under: Biología Molecular, Epidemiología, Infecciones del SNC, Infecciones parasitarias, Metodos diagnosticos, Sepsis, Update, Zoonosis.

Improved Method for the Detection and Quantification of Naegleria fowleri in Water and Sediment Using Immunomagnetic Separation and Real-Time PCR. The dangerous turn of “brain eating amoeba” in Sindh, Pakistan.


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