Identification of Low-Level Vancomycin Resistance in Staphylococcus aureus in the Era of Informatics

March 9, 2017 at 3:28 pm

Journal of Clinical Microbiology April 2016 V.54 N.4 P.836-839

Bradley A. Ford

Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA

Vancomycin-intermediate Staphylococcus aureus (VISA) and heteroresistant VISA (hVISA) are pathogens for which accurate antimicrobial susceptibility testing (AST) would rule out standard treatment with vancomycin. Unfortunately, AST for vancomycin is relatively slow and standard methods are unable to reliably detect VISA and hVISA. An article in this issue (C. A. Mather, B. J. Werth, S. Sivagnanam, D. J. SenGupta, and S. M. Butler-Wu, J Clin Microbiol 54:883–890, 2016, doi:http://dx.doi.org/10.1128/JCM.02428-15) describes a rapid whole-cell matrix-assisted laser desorption ionization–time of flight proxy susceptibility method that highlights current innovations and challenges with rapid AST, VISA/hVISA identification, and clinical bioinformatics.

PDF

http://jcm.asm.org/content/54/4/836.full.pdf

Advertisements

Entry filed under: Antimicrobianos, Bacterias, Bacteriemias, Metodos diagnosticos, REPORTS, Resistencia bacteriana, Update.

HIV Whole-Genome Sequencing Now: Answering Still-Open Questions Zika Virus: Diagnostics for an Emerging Pandemic Threat


Calendar

March 2017
M T W T F S S
« Feb   Apr »
 12345
6789101112
13141516171819
20212223242526
2728293031  

Most Recent Posts


%d bloggers like this: