Corticosteroids in treating CAP – has the time really come.

May 9, 2017 at 8:25 am

Clinical Microbiology and Infection May 2017 V.23 N.5

Blot, A. Salmon-Rousseau, P. Chavanet, L. Piroth*

Departement d’Infectiologie, Centre Hospitalier Universitaire, Dijon, France

Whether corticosteroids should be used in the treatment of severe community-acquired pneumonia (CAP) is still a matter of debate.

This question is all the more relevant as pneumonia remains a leading cause of death worldwide.

Severe CAP is associated with an increase in pulmonary and circulatory cytokines, which may be associated with treatment failure, especially in bacteraemic pneumococcal pneumonia.

Thus corticosteroids, which suppress inflammatory reactions and prevent the migration of inflammatory cells to tissues, may be of particular interest in the treatment of such severe pneumonias …

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http://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(16)30388-3/pdf

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Entry filed under: Antimicrobianos, Bacterias, Bacteriemias, F.O.D, Infecciones respiratorias, Metodos diagnosticos, REPORTS, Sepsis, Update.

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