PERCH in Perspective: What Can It Teach Us About Pneumonia Etiology in Children?

June 3, 2017 at 1:41 pm

Clinical Infectious Diseases June 15, 2017 V.64 Suppl.3

Keith P. Klugman; Gail L. Rodgers

The pneumonia team at the Bill & Melinda Gates Foundation congratulates the Pneumonia Etiology Research for Child Health (PERCH) study on delivering on their grant to collect high-quality data from thousands of children with World Health Organization–defined severe and very severe pneumonia and from controls in 9 diverse sites in 7 low- and middle-income countries. This supplement sets the foundation to understanding this complex study by providing an in-depth description of the study methodology, including discussion of key aspects such as antibiotic pretreatment, chest radiograph interpretation, utility of induced sputum in children, measurement of pathogen density, and use of C-reactive protein, and how these affect pneumonia etiology.

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Entry filed under: Antimicrobianos, Bacterias, Bacteriemias, Epidemiología, Infecciones respiratorias, Infecciones virales, Inmunizaciones, Metodos diagnosticos, Sepsis, Update.

Introduction to the Epidemiologic Considerations, Analytic Methods, and Foundational Results From the Pneumonia Etiology Research for Child Health Study The Enduring Challenge of Determining Pneumonia Etiology in Children: Considerations for Future Research Priorities


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