Standardization of Laboratory Methods for the PERCH Study

June 3, 2017 at 1:48 pm

Clinical Infectious Diseases June 15, 2017 V.64 Suppl.3

Amanda J. Driscoll; Ruth A. Karron; Susan C. Morpeth; Niranjan Bhat; Orin S. Levine …

The Pneumonia Etiology Research for Child Health study was conducted across 7 diverse research sites and relied on standardized clinical and laboratory methods for the accurate and meaningful interpretation of pneumonia etiology data. Blood, respiratory specimens, and urine were collected from children aged 1–59 months hospitalized with severe or very severe pneumonia and community controls of the same age without severe pneumonia and were tested with an extensive array of laboratory diagnostic tests. A standardized testing algorithm and standard operating procedures were applied across all study sites. Site laboratories received uniform training, equipment, and reagents for core testing methods. Standardization was further assured by routine teleconferences, in-person meetings, site monitoring visits, and internal and external quality assurance testing. Targeted confirmatory testing and testing by specialized assays were done at a central reference laboratory.

PDF

https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/cid/64/suppl_3/10.1093_cid_cix081/5/cix081.pdf?Expires=1496599965&Signature=U9h8pFYoURsVQ881EiCvBV7SnlVhp4F8zpdzQKqtAAeLwIscqEskTZDIuZZhqeRuSxufoIvMDC12lYaHjBI8GWc9qCRR6CXKnKAjChIkxtbgY4XEjJt4qFoq09Aj8FyWK0kSqoCzsBUhk1l7Lwxi5iHw1aO77A7sI5KbAL-rWH-KFErv1C5qCTQBmSeI2DDykGKbheDT8o23uSqaZTygDzysAtWaAodCDrUa-Ugf73HL8DWQlBOVVJl7eAMLNoamCLcHcdr8CTmALtTP50KH~LEQvSnG8SRmaeqfEk4N~f6FLuSzHMGYbvfDG9kVzMUWeGe-hDjtUWPTwqozPPWUxg__&Key-Pair-Id=APKAIUCZBIA4LVPAVW3Q

Advertisements

Entry filed under: Antimicrobianos, Bacterias, Bacteriemias, Epidemiología, Infecciones respiratorias, Infecciones virales, Inmunizaciones, Metodos diagnosticos, Sepsis, Update.

Data Management and Data Quality in PERCH, a Large International Case-Control Study of Severe Childhood Pneumonia Standardized Interpretation of Chest Radiographs in Cases of Pediatric Pneumonia From the PERCH Study


Calendar

June 2017
M T W T F S S
« May   Jul »
 1234
567891011
12131415161718
19202122232425
2627282930  

Most Recent Posts


%d bloggers like this: