Clinical and Microbiological Characteristics of Bacteroides Prosthetic Joint Infections.

June 20, 2017 at 5:39 pm

J Bone Jt Infect. 2017 Mar 19;2(3):122-126.

Shah N1, Osmon D1, Tande AJ1, Steckelberg J1, Sierra R2, Walker R1, Berbari EF1.

Author information

1 Division of Infectious Disease, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

2 Department of Orthopedic Surgery, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

Abstract

Clinical and microbiological characteristics of patients with Bacteroides prosthetic joint infection (PJI) have not been well described in the literature.

The aim of this retrospective cohort study was to assess the outcome of patients with Bacteroides PJI and to review risk factors associated with failure of therapy.

Between 1/1969 and 12/2012, 20 episodes of Bacteroides PJI in 17 patients were identified at our institution. The mean age of the patients in this cohort at the time of diagnosis was 55.6 years; 59% (n=10) had knee involvement. Twenty four percent (n=4) had diabetes mellitus, and 24% had a history of either gastrointestinal (GI) or genitourinary (GU) pathology prior to the diagnosis of PJI. Thirty five percent (n=6) were immunosuppressed.

The initial medical/surgical strategy was resection arthroplasty (n=9, 50%) or debridement and implant retention (n=5, 28%). Thirty seven percent (n=7) were treated with metronidazole. Eighty percent (n=4) of patients that failed therapy had undergone debridement and retention of their prosthesis, as compared to none of those treated with resection arthroplasty. Seventy percent (n=14) of patient episodes were infection free at their last date of follow up.

In conclusion, a significant proportion of patients with Bacteroides PJI are immunosuppressed and have an underlying GI or GU tract pathology. Retention and debridement of the prosthesis is associated with a higher risk of treatment failure.

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441143/pdf/jbjiv02p0122.pdf

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Entry filed under: Antimicrobianos, Bacterias, Biología Molecular, Epidemiología, FIEBRE en el POSTOPERATORIO, Health Care-Associated Infections, Infecciones nosocomiales, Infecciones osteo-articulares-musculares, Infecciones relacionadas a prótesis, Infecciones sitio quirurgico, Metodos diagnosticos, Profilaxis Antibiótica en Cirugía - PAC, REPORTS, Resistencia bacteriana, Sepsis, Update.

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