Archive for July 12, 2017

Serious Bacterial Infections Acquired During Treatment of Patients Given a Diagnosis of Chronic Lyme Disease – United States.

Morbidity and Mortality Weekly Report. June 16, 2017 V.66 N.23 P.607-609.

Marzec NS, Nelson C, Waldron PR, Blackburn BG, Hosain S, Greenhow T, Green GM, Lomen-Hoerth C, Golden M, Mead PS.

Abstract

The term “chronic Lyme disease” is used by some health care providers as a diagnosis for various constitutional, musculoskeletal, and neuropsychiatric symptoms (1,2).

Patients with a diagnosis of chronic Lyme disease have been provided a wide range of medications as treatment, including long courses of intravenous (IV) antibiotics (3,4).

Studies have not shown that such treatments lead to substantial long-term improvement for patients, and they can be harmful (1,5).

This report describes cases of septic shock, osteomyelitis, Clostridium difficile colitis, and paraspinal abscess resulting from treatments for chronic Lyme disease.

Patients, clinicians, and public health practitioners should be aware that treatments for chronic Lyme disease can carry serious risks.

PDF

https://www.cdc.gov/mmwr/volumes/66/wr/pdfs/mm6623a3.pdf

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July 12, 2017 at 3:28 pm

Amoxicillin and Ceftriaxone as Treatment Alternatives to Penicillin for Maternal Syphilis.

Emerging Infectious Diseases. May 2017 V.23 N.5 P.827-829.

Katanami Y, Hashimoto T, Takaya S, Yamamoto K, Kutsuna S, Takeshita N, Hayakawa K, Kanagawa S, Ohmagari N.

Abstract

There is no proven alternative to penicillin for treatment of maternal syphilis. We report 2 case-patients with maternal syphilis who were successfully treated without penicillin.

We used amoxicillin and probenecid for the first case-patient and amoxicillin, probenecid, and ceftriaxone for the second case-patient.

PDF

https://wwwnc.cdc.gov/eid/article/23/5/pdfs/16-1936.pdf

July 12, 2017 at 3:26 pm

Surveillance and outbreak report LEGIONNAIRES’ DISEASE IN EUROPE, 2011 TO 2015

Eurosurveillance July 06, 2017 V.22 N.27

J Beauté 1 2 , on behalf of the European Legionnaires’ Disease Surveillance Network 3

  1. European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden
  2. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
  3. The members of the network are listed at the end of the article

Under the coordination of the European Centre for Disease Prevention and Control (ECDC), the European Legionnaires’ disease Surveillance Network (ELDSNet) conducts surveillance of Legionnaires’ disease (LD) in Europe. Between 2011 and 2015, 29 countries reported 30,532 LD cases to ECDC (28,188 (92.3%) confirmed and 2,344 (7.7%) probable). Four countries (France, Germany, Italy and Spain) accounted for 70.3% of all reported cases, although their combined populations represented only 49.9% of the study population. The age-standardised rate of all cases increased from 0.97 cases/100,000 population in 2011 to 1.30 cases/100,000 population in 2015, corresponding to an annual average increase of 0.09 cases/100,000 population (95%CI 0.02–0.14; p = 0.02). Demographics and infection setting remained unchanged with ca 70% of cases being community-acquired and 80% occurring in people aged 50 years and older. Clinical outcome was known for 23,164 cases, of whom 2,161 (9.3%) died. The overall case fatality ratio decreased steadily from 10.5% in 2011 to 8.1% in 2015, probably reflecting improved reporting completeness. Five countries (Austria, Czech Republic, Germany, Italy, and Norway) had increasing age-standardised LD notification rates over the 2011−15 period, but there was no increase in notification rates in countries where the 2011 rate was below 0.5/100,000 population….

FULL TEXT

http://eurosurveillance.org/ViewArticle.aspx?ArticleId=22829

PDF

http://eurosurveillance.org/images/dynamic/EE/V22N27/art22829.pdf

July 12, 2017 at 8:20 am


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