The association between vitamin D levels and recurrent group A streptococcal tonsillopharyngitis in adults.

August 1, 2017 at 3:38 pm

International  Journal of Infectious Diseases October 2012 V.16 N.10 e735-7388.

Nseir W1, Mograbi J, Abu-Rahmeh Z, Mahamid M, Abu-Elheja O, Shalata A.

Author information

1 Department of Internal Medicine, Infectious Disease Unit, Holy Family Hospital, Nazareth, Israel. w.nseir@yahoo.com

Abstract

OBJECTIVES:

To determine the association between recurrent group A streptococcal (GAS) tonsillopharyngitis and serum 25-hydroxy (25(OH)) vitamin D among adult subjects.

METHODS:

Adult patients with tonsillopharyngitis between January 2007 and December 2009 were reviewed and identified retrospectively. Cases with a medical history of recurrent GAS tonsillopharyngitis were compared to age- and gender-matched individuals without a medical history of GAS tonsillopharyngitis. Recurrent tonsillopharyngitis was defined as three or more episodes of GAS tonsillopharyngitis per year for a period of two consecutive years.

RESULTS:

Fifty-four cases with recurrent GAS tonsillopharyngitis and 50 controls were enrolled. There were no significant differences between cases and controls with regard to mean age (41 ± 13 vs. 42 ± 12 years; p=0.7) and male gender (55% vs. 54%; p=0.6). Mean serum levels of 25(OH) vitamin D among subjects with recurrent GAS tonsillopharyngitis were significantly lower from the controls (11.5 ng/ml ± 4.7 vs. 26 ng/ml ± 7; p=0.001). Multiple regression analysis showed that a serum 25(OH) vitamin D level <20 ng/ml was associated with recurrent GAS tonsillopharyngitis (odds ratio 1.62, 95% confidence interval 1.51-1.76; p < 0.001).

CONCLUSIONS:

Our findings indicate a link between vitamin D deficiency and the recurrence of GAS tonsillopharyngitis.

PDF

http://www.ijidonline.com/article/S1201-9712(12)01189-7/pdf

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Entry filed under: Antimicrobianos, Bacterias, Infecciones oro-faríngeas, Infecciones respiratorias, Metodos diagnosticos, REPORTS, Update.

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