Preventing Methicillin-Resistant Staphylococcus aureus (MRSA) Disease in Urban US Hospitals—Now for the Hard Part: More Evidence Pointing to the Community as the Source of MRSA Acquisition

September 27, 2017 at 8:47 am

Journal of Infectious Diseases June 1, 2017 V.215 N.11 P.1631–1633

EDITOR’S CHOICE

Susan M. Ray

Methicillin-resistant Staphylococcus aureus (MRSA) first emerged in the 1960s, shortly after the introduction of methicillin for therapeutic use [1].

Over the next 4 decades, MRSA spread worldwide and became endemic in hospitals in many countries [2]. In the 1990s, community- associated MRSA emerged as an epidemic of skin and soft-tissue infections in patients without any prior healthcare contact and was associated with serious morbidity and mortality [3, 4].

Although the earliest reports of community-associated MRSA disease in the United States were due to both USA400 and USA300, it was soon clear that USA300 was the epidemic community-associated MRSA clone of greatest importance in the United States, and it has persisted for well over a decade [5, 6].

By the mid-2000s, USA300 was noted to cause healthcare-associated disease [7], and in some urban centers it now accounts for up to 50% of nosocomial MRSA bacteremias [8] and a high proportion of cases of MRSA disease and colonization in long-term-care facilities [9, 10]….

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Entry filed under: Antimicrobianos, Bacterias, Bacteriemias, Biología Molecular, Epidemiología, Metodos diagnosticos, Resistencia bacteriana, Sepsis, Update.

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