Invasive streptococcal disease: a review for clinicians.

September 21, 2018 at 8:20 am

Br Med Bull. 2015 Sep;115(1):77-89.

Parks T1, Barrett L2, Jones N3.

Abstract

INTRODUCTION:

Streptococci are a genus of Gram-positive bacteria which cause diverse human diseases. Many of these species have the potential to cause invasive infection resulting from the presence of bacteria in a normally sterile site.

SOURCES OF DATA:

Original articles, reviews and guidelines.

AREAS OF AGREEMENT:

Invasive infection by a streptococcus species usually causes life-threatening illness. When measured in terms of deaths, disability and cost, these infections remain an important threat to health in the UK. Overall they are becoming more frequent among the elderly and those with underlying chronic illness. New observational evidence has become available to support the use of clindamycin and intravenous immunoglobulin in invasive Group A streptococcal disease.

AREAS OF CONTROVERSY:

Few interventions for the treatment and prevention of these infections have undergone rigorous evaluation in clinical trials. For example, the role of preventative strategies such as screening of pregnant women to prevent neonatal invasive Group B streptococcal disease needs to be clarified.

FUTURE PROSPECTS:

Studies of invasive streptococcal disease are challenging to undertake, not least because individual hospitals treat relatively few confirmed cases. Instead clinicians and scientists must work together to build national and international networks with the aim of developing a more complete evidence base for the treatment and prevention of these devastating infections.

abstract

https://academic.oup.com/bmb/article/115/1/77/260207

PDF (CLIC en PDF)

Advertisements

Entry filed under: Antimicrobianos, Bacterias, Bacteriemias, Biología Molecular, Epidemiología, FIEBRE y RASH, Infecciones emergentes, Infecciones en piel y tej blandos, Metodos diagnosticos, REPORTS, REVIEWS, Sepsis, Update.

Changes in the clinical and epidemiological features of group A streptococcal bacteraemia in Australia’s Northern Territory. Description of the Pathogenic Features of Streptococcus pyogenes Isolates from Invasive and Non-Invasive Diseases in Aichi, Japan.


Calendar

September 2018
M T W T F S S
« Aug   Oct »
 12
3456789
10111213141516
17181920212223
24252627282930

Most Recent Posts


%d bloggers like this: