Archive for December 26, 2018

Candida auris Sternal Osteomyelitis in a Man from Kenya Visiting Australia, 2015

Emerging Infectious Diseases January 2019 V.25  N.1

H. Heath et al.

In Australia in 2015, Candida auris sternal osteomyelitis was diagnosed in a 65-year-old man with a history of intensive care treatment in Kenya in 2012 and without a history of cardiac surgery.

The isolate was South Africa clade III.

Clinicians should note that C. auris can cause low-grade disease years after colonization.

PDF

https://wwwnc.cdc.gov/eid/article/25/1/pdfs/18-1321.pdf

December 26, 2018 at 3:48 pm

Clinical and Radiologic Characteristics of Human Metapneumovirus Infections in Adults, South Korea

Emerging Infectious Diseases January 2019 V.25  N.1

Koo et al.

Clinical features of human metapneumovirus (HMPV) infection have not been well documented for adults.

We investigated clinical and radiologic features of HMPV infection in 849 adults in a tertiary hospital in South Korea.

We classified patients into groups on the basis of underlying diseases:

immunocompetent patients,

solid tumor patients,

solid organ transplantation recipients,

hematopoietic stem cell transplant recipients,

hematologic malignancy patients, and

patients receiving long-term steroid treatment.

Of 849 HMPV-infected patients, 756 had community-acquired infections, 579 had pneumonia, and 203 had infections with other pathogens.

Mortality rates were highest in hematopoietic stem cell transplantation recipients (22% at 30 days).

Older age, current smoking, and underlying disease were associated with HMPV pneumonia.

Body mass index and an immunocompromised state were associated with 30-day mortality rates in HMPV-infected patients.

Bronchial wall thickening, ground-glass opacity, and ill-defined centrilobular nodules were common computed tomography findings for HMPV pneumonia.

Macronodules and consolidation were observed in <50% of patients.

PDF

https://wwwnc.cdc.gov/eid/article/25/1/pdfs/18-1131.pdf

December 26, 2018 at 3:45 pm

Deadly Marburg Virus Found in Sierra Leone Bats

Centers for Disease Control and Prevention (Estados Unidos)

First time this Ebola-like virus identified in West Africa

Scientists have discovered live Marburg virus in fruit bats in Sierra Leone – the first time the deadly virus has been found in West Africa.

Five Egyptian rousette fruit bats tested positive for active Marburg virus infection. Scientists caught the bats separately at locations in three health districts: Moyamba, Koinadugu and Kono.

There have been no reported cases of people sick with Marburg in Sierra Leone, but the virus’s presence in bats means people nearby could be at risk for contracting Marburg virus.

Marburg virus is a cousin to Ebola virus that causes a similar, often fatal disease in people….

FULL TEXT

https://www.cdc.gov/media/releases/2018/p1220-marburg-found-in-bats.html

December 26, 2018 at 8:54 am

Infections After Receipt of Bacterially Contaminated Umbilical Cord Blood–Derived Stem Cell Products for Other Than Hematopoietic or Immunologic Reconstitution — United States, 2018

Morbidity and Mortality Weekly Report December 21, 2018  V.67 N.50 P.1397–1399

Infections After Receipt of Bacterially Contaminated Umbilical Cord Blood–Derived Stem Cell Products for Other Than Hematopoietic or Immunologic Reconstitution — United States, 2018

The only Food and Drug Administration (FDA)–approved stem cell products are derived from umbilical cord blood, and their only approved use is hematopoietic and immunologic reconstitution (1).

On September 17, 2018, the Texas Department of State Health Services received notification of Enterobacter cloacae and Citrobacter freundii bloodstream infections in three patients who had received injections or infusions of non-FDA–approved umbilical cord blood-derived stem cell products processed by Genetech, Inc., and distributed by Liveyon, LLC, for other than hematopoietic or immunologic reconstitution at an outpatient clinic on September 12.

Patient isolates of E. cloacae had identical pulsed-field gel electrophoresis patterns, suggesting a common source …

PDF

https://www.cdc.gov/mmwr/volumes/67/wr/pdfs/mm6750a5-H.pdf

December 26, 2018 at 8:52 am


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