Characterization of Chemical Meningitis after Neurological Surgery

April 2, 2019 at 6:10 pm

Clinical Infectious Diseases January 2001 V.32 N.2 P.179-185

Pierre Forgacs; Carl A. Geyer; Stephen R. Freidberg

We reviewed the records of 70 consecutive adult patients with meningitis after a neurosurgical procedure, to determine the characteristics that might help to distinguish a sterile postoperative chemical meningitis from bacterial infection. The spinal fluid profiles in bacterial and chemical meningitis are similar. The exceptions are that a spinal fluid white blood cell count >7500/µL (7500 × 106/L) and a glucose level of <10 mg/dL were not found in any case of chemical meningitis. The clinical setting and clinical manifestations were distinct enough that no antibiotic was administered after lumbar puncture to 30 (43%) of the 70 patients with postoperative meningitis. Chemical meningitis was infrequent after surgery involving the spine and sinuses. Patients with chemical meningitis did not have purulent wound drainage or significant wound erythema or tenderness, coma, new focal neurological findings, or onset of a new seizure disorder. They rarely had temperatures >39.4°C or cerebrospinal fluid rhinorrhea or otorrhea.

FULL TEXT

https://academic.oup.com/cid/article/32/2/179/319157

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Entry filed under: Antimicrobianos, Bacterias, Bacteriemias, Biología Molecular, BIOMARCADORES, Epidemiología, FIEBRE en el POSTOPERATORIO, Health Care-Associated Infections, Infecciones del SNC, Infecciones nosocomiales, Infecciones relacionadas a prótesis, Infecciones sitio quirurgico, Metodos diagnosticos, REPORTS, Resistencia bacteriana, Sepsis, Update.

Meningitis postquirúrgica. Características diferenciales de la meningitis aséptica post-quirúrgica Predictive Value of Cerebrospinal Fluid (CSF) Lactate Level vs CSF-Blood Glucose Ratio for the Diagnosis of Bacterial Meningitis Following Neurosurgery


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