Posts filed under ‘Biología Molecular’

Diagnosis and Treatment of Adults with Community-acquired Pneumonia

Am J Respir Crit Care Med October 1, 2019 V.200 N.7 P.e45–e67

An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America

FULL TEXT

https://www.atsjournals.org/doi/10.1164/rccm.201908-1581ST

PDF

https://www.atsjournals.org/doi/pdf/10.1164/rccm.201908-1581ST

November 10, 2019 at 11:36 am

Effect of procalcitonin-guided antibiotic treatment on clinical outcomes in intensive care unit patients with infection and sepsis patients: a patient-level meta-analysis of randomized trials.

Crit Care. 2018;22:191. 

Wirz Y, Meier MA, Bouadma L, et al.

FULL TEXT 

https://ccforum.biomedcentral.com/articles/10.1186/s13054-018-2125-7

 

November 10, 2019 at 11:35 am

Surviving Sepsis Campaign: International guidelines for management of sepsis and septic shock: 2016.

Crit Care Med. 2017;45:486-552. 

Rhodes A, Evans LE, Alhazzani W, et al.

FULL TEXT

https://journals.lww.com/ccmjournal/fulltext/2017/03000/Surviving_Sepsis_Campaign__International.15.aspx

PDF (CLIC DOWNLOAD)

November 10, 2019 at 11:33 am

Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the Infectious Diseases Society of America and the American Thoracic Society.

Clin Infect Dis. 2016;63:e61-e111. 

Kalil AC, Metersky ML, Klompas M, et al.

FULL TEXT

https://academic.oup.com/cid/article/63/5/e61/2237650

PDF (CLIC DOWNLOAD)

https://www.medscape.com/viewarticle/919985?nlid=132279_804&src=WNL_mdplsfeat_191029_mscpedit_infd&uac=54104DR&spon=3&impID=2148248&faf=1

November 10, 2019 at 11:31 am

A New Perspective on HIV Diagnostics: Reinterpretation in the Age of Early Treatment

Clin. Microbiol. October 2019 V.57 N.10

Commentary

Early treatment of HIV infection with antiretroviral therapy in recently identified HIV-infected individuals reduces viral replication and decreases the risk of transmission.

The screening and supplemental, confirmatory assays used to identify infection are influenced by early treatment and may obscure a clear diagnosis of HIV infection.

In this issue of the Journal of Clinical Microbiology, Manak et al. demonstrate the impact of antiretroviral therapy on the evolution of biomarkers that have traditionally been used for identifying HIV infection

abstract

https://jcm.asm.org/content/57/10/e00978-19.abstract?etoc

PDF

https://jcm.asm.org/content/jcm/early/2019/07/26/JCM.00978-19.full.pdf

September 24, 2019 at 3:18 pm

Control and Elimination of Extensively Drug-Resistant Acinetobacter baumanii in an Intensive Care Unit

Emerging Infectious Diseases October 2019 V.25 N.10

We decreased antimicrobial drug consumption in an intensive care unit in Lebanon by changing to colistin monotherapy for extensively drug-resistant Acinetobacter baumanii infections. We saw a 78% decrease of A. baumanii in sputum and near-elimination of blaoxa-23-carrying sequence type 2 clone over the 1-year study. Non–A. baumanii multidrug-resistant infections remained stable.

FULL TEXT

https://wwwnc.cdc.gov/eid/article/25/10/18-1626_article?deliveryName=DM9244

PDF (CLIC en DOWNLOADS / ARTICLE)

September 23, 2019 at 10:00 am

Risk Factors for Carbapenem-Resistant Pseudomonas aeruginosa, Zhejiang Province, China

Emerging Infectious Diseases October 2019 V.25 N.10

Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a public health concern worldwide, but comprehensive analysis of risk factors for CRPA remains limited in China.

We conducted a retrospective observational study of carbapenem resistance in 71,880 P. aeruginosa isolates collected in Zhejiang Province during 2015–2017.

We analyzed risk factors for CRPA, including the type of clinical specimen; the year, season, and region in which it was collected; patient information, including age, whether they were an outpatient or inpatient, and whether inpatients were in the intensive care unit or general ward; and the level of hospital submitting isolates.

We found CRPA was more prevalent among isolates from patients >60 years of age and in inpatients, especially in intensive care units. In addition, specimen types and seasons in which they were collected were associated with higher rates of CRPA.

Our findings can help hospitals reduce the spread of P. aeruginosa and optimize antimicrobial drug use.

FULL TEXT

https://wwwnc.cdc.gov/eid/article/25/10/18-1699_article?deliveryName=DM9244

PDF (CLIC en DOWNLOADS / ARTICLE)

September 23, 2019 at 9:59 am

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