Posts filed under ‘CONSENSOS’

REVIEW – Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents.

J Hospital Infect. March 2020 V.104 N.3 P.246–251.

Kampf G,Todt D, Pfaender S, Steinmann E.

Actualmente, la aparición de un nuevo coronavirus humano, SARS-CoV-2, se ha convertido en un problema de salud global que causa infecciones graves del tracto respiratorio en humanos.

Las transmisiones de persona a persona se han descrito con tiempos de incubación de entre 2 y 10 días, lo que facilita su propagación a través de gotas, manos o superficies contaminadas.

Por lo tanto, revisaron la literatura sobre toda la información disponible sobre la persistencia de coronavirus humanos y veterinarios en superficies inanimadas, así como las estrategias de inactivación con agentes biocidas utilizados para la desinfección química, p. ej. en instalaciones sanitarias.

El análisis de 22 estudios revela que los coronavirus humanos como el coronavirus del Síndrome Respiratorio Agudo Severo (SARS), el coronavirus del Síndrome Respiratorio del Medio Oriente (MERS) o los coronavirus humanos endémicos (HCoV) pueden persistir en superficies inanimadas como metal, vidrio o plástico por hasta 9 días, pero se puede inactivar eficientemente mediante procedimientos de desinfección de superficie con:

etanol al 62–71%,

peróxido de hidrógeno al 0.5% o

hipoclorito de sodio al 0.1% en 1 minuto.

Otros agentes biocidas como el cloruro de benzalconio al 0.05–0.2% o el digluconato de clorhexidina al 0.02% son menos efectivos.

Como no hay terapias específicas disponibles para el SARS-CoV-2, la contención temprana y la prevención de una mayor propagación serán cruciales para detener el brote en curso y controlar este nueva infección.

FULL TEXT

https://www.journalofhospitalinfection.com/article/S0195-6701(20)30046-3/fulltext

PDF (CLIC en PDF)

 

April 4, 2020 at 10:34 am

CDC – Coronavirus Disease 2019 (COVID-19)

CDC – Coronavirus Disease 2019 (COVID-19)

https://www.cdc.gov/coronavirus/2019-ncov/index.html

https://www.cdc.gov/coronavirus/2019-ncov/index-sp.html

El 11/02/2020, la Organización Mundial de la Salud anunció un nombre oficial para la enfermedad que está causando el brote actual de la enfermedad por coronavirus, COVID-19.

SINTOMAS

https://www.cdc.gov/coronavirus/2019-ncov/about/symptoms-sp.html

PREVENCION y TRATAMIENTO

https://www.cdc.gov/coronavirus/2019-ncov/about/prevention-treatment-sp.html

PREVENIR PROPAGACION del 2019-nCoV

https://www.cdc.gov/coronavirus/2019-ncov/hcp/guidance-prevent-spread-sp.html

PREGUNTAS FRECUENTES SOBRE EL 2019-nCoV

https://www.cdc.gov/coronavirus/2019-ncov/faq-sp.html

MAS INFORMACION (en inglés)

https://www.cdc.gov/coronavirus/2019-ncov/index.html

 

About Coronavirus Disease 2019 (COVID-19)

https://www.cdc.gov/coronavirus/2019-ncov/about/index.html

-How COVID-19 Spreads

https://www.cdc.gov/coronavirus/2019-ncov/about/transmission.html

-Symptoms

https://www.cdc.gov/coronavirus/2019-ncov/about/symptoms.html

-CDC Tests for COVID-19

https://www.cdc.gov/coronavirus/2019-ncov/about/testing.html

-Laboratory Work

https://www.cdc.gov/coronavirus/2019-ncov/about/laboratory-work.html

-Prevention & Treatment

https://www.cdc.gov/coronavirus/2019-ncov/about/prevention-treatment.html

-What to Do If You Are Sick With Coronavirus Disease 2019 (COVID-19)

https://www.cdc.gov/coronavirus/2019-ncov/about/steps-when-sick.html

-Frequently Asked Questions and Answers

https://www.cdc.gov/coronavirus/2019-ncov/faq.html

– What you need to know (Fact Sheet)

https://www.cdc.gov/coronavirus/2019-ncov/downloads/2019-ncov-factsheet-sp.pdf

-What to do if you are sick (Fact Sheet)

https://www.cdc.gov/coronavirus/2019-ncov/downloads/sick-with-2019-nCoV-fact-sheet-sp.pdf

Information for Healthcare Professionals from CDC

https://www.cdc.gov/coronavirus/2019-ncov/hcp/index.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Fguidance-hcp.html

Current Interim Guidance (Orientación provisional actual):

-Evaluating and Reporting Persons Under Investigation (PUI)

https://www.cdc.gov/coronavirus/2019-nCoV/hcp/clinical-criteria.html

https://www.cdc.gov/coronavirus/2019-ncov/hcp/identify-assess-flowchart.html

https://www.cdc.gov/coronavirus/2019-ncov/php/reporting-pui.html

-Healthcare Infection Control Guidance

https://www.cdc.gov/coronavirus/2019-nCoV/hcp/infection-control.html

https://www.cdc.gov/coronavirus/2019-ncov/hcp/infection-prevention-control-faq.html

-Clinical Care Guidance

https://www.cdc.gov/coronavirus/2019-ncov/hcp/clinical-guidance-management-patients.html

-Home Care Guidance

https://www.cdc.gov/coronavirus/2019-ncov/hcp/guidance-home-care.html

https://www.cdc.gov/coronavirus/2019-ncov/hcp/guidance-prevent-spread.html

https://www.cdc.gov/coronavirus/2019-ncov/hcp/disposition-in-home-patients.html

-Guidance for EMS (Emergency Medical Services)

https://www.cdc.gov/coronavirus/2019-ncov/hcp/guidance-for-ems.html

-Healthcare Personnel with Potential Exposure Guidance

https://www.cdc.gov/coronavirus/2019-ncov/hcp/guidance-risk-assesment-hcp.html

Other Resources:

-COVID-19 Publications

https://www.cdc.gov/coronavirus/2019-ncov/publications.html

-Healthcare Preparedness Tools

https://www.cdc.gov/coronavirus/2019-ncov/hcp/preparedness-checklists.html

-Health Alert Network (HAN): Update and Interim Guidance on Outbreak of Coronavirus Disease 2019

https://emergency.cdc.gov/han/han00427.asp

Resources for Healthcare Professionals Caring for COVID-19 Patients:

-What Healthcare Providers Should Know

https://www.cdc.gov/coronavirus/2019-ncov/hcp/caring-for-patients.html

-Frequently Asked Questions for Healthcare Providers

https://www.cdc.gov/coronavirus/2019-ncov/hcp/faq.html

Clinical Care:

-Clinical Care Guidance

https://www.cdc.gov/coronavirus/2019-ncov/hcp/clinical-guidance-management-patients.html

-Disposition of Hospitalized Patients with COVID-2019

https://www.cdc.gov/coronavirus/2019-ncov/hcp/disposition-hospitalized-patients.html

Infection Control:

-Infection Control

https://www.cdc.gov/coronavirus/2019-nCoV/hcp/infection-control.html

-Frequently Asked Questions: Healthcare Infection Prevention and Control

https://www.cdc.gov/coronavirus/2019-ncov/hcp/infection-prevention-control-faq.html

Supply of Personal Protective Equipment (Suministro de equipo de protección personal):

-Healthcare Supply of Personal Protective Equipment

https://www.cdc.gov/coronavirus/2019-ncov/hcp/healthcare-supply-ppe.html

-Strategies for Optimizing Supply of N95 Respirators

https://www.cdc.gov/coronavirus/2019-ncov/hcp/respirator-supply-strategies.html

-FAQ about Respirators

https://www.cdc.gov/coronavirus/2019-ncov/hcp/respirator-use-faq.html

February 19, 2020 at 8:02 am

Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America

American Journal of Respiratory and Critical Care Medicine October 1, 2019 V.200 N.7

Background

This document provides evidence-based clinical practice guidelines on the management of adult patients with community-acquired pneumonia.

Methods

A multidisciplinary panel conducted pragmatic systematic reviews of the relevant research and applied Grading of Recommendations, Assessment, Development, and Evaluation methodology for clinical recommendations.

Results

The panel addressed 16 specific areas for recommendations spanning questions of diagnostic testing, determination of site of care, selection of initial empiric antibiotic therapy, and subsequent management decisions. Although some recommendations remain unchanged from the 2007 guideline, the availability of results from new therapeutic trials and epidemiological investigations led to revised recommendations for empiric treatment strategies and additional management decisions.

Conclusions

The panel formulated and provided the rationale for recommendations on selected diagnostic and treatment strategies for adult patients with community-acquired pneumonia.

FULL TEXT

https://www.atsjournals.org/doi/10.1164/rccm.201908-1581ST#_i6

PDF

https://www.atsjournals.org/doi/pdf/10.1164/rccm.201908-1581ST

January 21, 2020 at 3:54 pm

2018 recommendations for the management of community acquired pneumonia.

J Bras Pneumol. September-October 2018 V.;44 N.5 P.405-423.   

Corrêa RA1, Costa AN2, Lundgren F3, Michelin L4, Figueiredo MR5, Holanda M6, Gomes M7, Teixeira PJZ8, Martins R9, Silva R10, Athanazio RA2, Silva RMD11, Pereira MC12.

Abstract

Community-acquired pneumonia (CAP) is the leading cause of death worldwide. Despite the vast diversity of respiratory microbiota, Streptococcus pneumoniae remains the most prevalent pathogen among etiologic agents. Despite the significant decrease in the mortality rates for lower respiratory tract infections in recent decades, CAP ranks third as a cause of death in Brazil. Since the latest Guidelines on CAP from the Sociedade Brasileira de Pneumologia e Tisiologia (SBPT, Brazilian Thoracic Association) were published (2009), there have been major advances in the application of imaging tests, in etiologic investigation, in risk stratification at admission and prognostic score stratification, in the use of biomarkers, and in the recommendations for antibiotic therapy (and its duration) and prevention through vaccination. To review these topics, the SBPT Committee on Respiratory Infections summoned 13 members with recognized experience in CAP in Brazil who identified issues relevant to clinical practice that require updates given the publication of new epidemiological and scientific evidence. Twelve topics concerning diagnostic, prognostic, therapeutic, and preventive issues were developed. The topics were divided among the authors, who conducted a nonsystematic review of the literature, but giving priority to major publications in the specific areas, including original articles, review articles, and systematic reviews. All authors had the opportunity to review and comment on all questions, producing a single final document that was approved by consensus

PDF

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467584/pdf/1806-3713-jbpneu-44-05-00405.pdf

January 18, 2020 at 12:22 pm

Management of community-acquired pneumonia in adults: 2016 guideline update from the Dutch Working Party on Antibiotic Policy (SWAB) and Dutch Association of Chest Physicians (NVALT).

Neth J Med. January 2018 V.76 N.1 P.:4-13.

Wiersinga WJ1, Bonten MJ, Boersma WG, Jonkers RE, Aleva RM, Kullberg BJ, Schouten JA, Degener JE, van de Garde EMW, Verheij TJ, Sachs APE, Prins JM.

Abstract

The Dutch Working Party on Antibiotic Policy in collaboration with the Dutch Association of Chest Physicians, the Dutch Society for Intensive Care and the Dutch College of General Practitioners have updated their evidence-based guidelines on the diagnosis and treatment of community-acquired pneumonia (CAP) in adults who present to the hospital. This 2016 update focuses on new data on the aetiological and radiological diagnosis of CAP, severity classification methods, initial antibiotic treatment in patients with severe CAP and the role of adjunctive corticosteroids. Other parts overlap with the 2011 guideline. Apart from the Q fever outbreak in the Netherlands (2007-2010) no other shifts in the most common causative agents of CAP or in their resistance patterns were observed in the last five years. Low-dose CT scanning may ultimately replace the conventional chest X-ray; however, at present, there is insufficient evidence to advocate the use of CT scanning as the new standard in patients evaluated for CAP. A pneumococcal urine antigen test is now recommended for all patients presenting with severe CAP; a positive test result can help streamline therapy once clinical stability has been reached and no other pathogens have been detected. Coverage for atypical microorganisms is no longer recommended in empirical treatment of severe CAP in the non-intensive care setting. For these patients (with CURB-65 score >2 or Pneumonia Severity Index score of 5) empirical therapy with a 2nd/3rd generation cephalosporin is recommended, because of the relatively high incidence of Gram-negative bacteria, and to a lesser extent S. aureus. Corticosteroids are not recommended as adjunctive therapy for CAP

PDF

http://www.njmonline.nl/getpdf.php?id=1933

January 18, 2020 at 12:21 pm

International consensus guidelines for the optimal use of the polymyxins

Pharmacotherapy. January 2019 V.39 N.1 P.10-39.

International consensus guidelines for the optimal use of the polymyxins: Endorsed by the American College of Clinical Pharmacy (ACCP), European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Society of America (IDSA), International Society for Anti-infective Pharmacology (ISAP), Society of Critical Care Medicine (SCCM), and Society of Infectious Diseases Pharmacists (SIDP).

Tsuji BT, Pogue JM, Zavascki AP, Paul M, Daikos GL, Forrest A, et al.

The polymyxin antibiotics colistin (polymyxin E) and polymyxin B became available in the 1950s and thus did not undergo contemporary drug development procedures. Their clinical use has recently resurged, assuming an important role as salvage therapy for otherwise untreatable gram‐negative infections.

Since their reintroduction into the clinic, significant confusion remains due to the existence of several different conventions used to describe doses of the polymyxins, differences in their formulations, outdated product information, and uncertainties about susceptibility testing that has led to lack of clarity on how to optimally utilize and dose colistin and polymyxin B.

We report consensus therapeutic guidelines for agent selection and dosing of the polymyxin antibiotics for optimal use in adult patients, as endorsed by the American College of Clinical Pharmacy (ACCP), Infectious Diseases Society of America (IDSA), International Society of Anti‐Infective Pharmacology (ISAP), Society for Critical Care Medicine (SCCM), and Society of Infectious Diseases Pharmacists (SIDP).

The European Society for Clinical Microbiology and Infectious Diseases (ESCMID) endorses this document as a consensus statement.

The overall conclusions in the document are endorsed by the European Committee on Antimicrobial Susceptibility Testing (EUCAST). We established a diverse international expert panel to make therapeutic recommendations regarding the pharmacokinetic and pharmacodynamic properties of the drugs and pharmacokinetic targets, polymyxin agent selection, dosing, dosage adjustment and monitoring of colistin and polymyxin B, use of polymyxin‐based combination therapy, intrathecal therapy, inhalation therapy, toxicity, and prevention of renal failure.

The treatment guidelines provide the first ever consensus recommendations for colistin and polymyxin B therapy that are intended to guide optimal clinical use…..

FULL TEXT

https://accpjournals.onlinelibrary.wiley.com/doi/full/10.1002/phar.2209

PDF

January 16, 2020 at 3:59 pm

Sepsis and septic shock: Guideline-based management

Cleveland Clinic Journal of Medicine January 2020 V.87 N.1 P.53-64

La sepsis es una disfunción orgánica potencialmente mortal que resulta de la respuesta orgánica a la infección. Requiere reconocimiento rápido, antibióticos apropiados en tiempo y dosis, apoyo hemodinámico cuidadoso y control de la fuente de infección.

Con la tendencia en el manejo alejándose de la atención protocolizada y en favor de la atención habitual adecuada, es fundamental comprender la fisiología de la sepsis y las pautas de mejores prácticas.

abstract

https://www.ccjm.org/content/87/1/53.abstract?etoc

PDF

https://www.ccjm.org/content/ccjom/87/1/53.full.pdf

January 11, 2020 at 9:26 am

Older Posts


Calendar

April 2020
M T W T F S S
 12345
6789101112
13141516171819
20212223242526
27282930  

Posts by Month

Posts by Category