Posts filed under ‘CONSENSOS’

Vaccination Guidelines for Patients with Immune-Mediated Disorders on Immunosuppressive Therapies-Executive Summary. 

Journal of the Canadian Association of Gastroenterology  December 2019 V.2 N.4 P.149-152.

Papp KA, Haraoui B, Kumar D, Marshall JK, Bissonnette R, Bitton A, et al.

The use of immunosuppressive therapies for immune-mediated disease (IMD) is associated with an elevated risk of infections and related comorbidities. While many infectious diseases can generally be prevented by vaccines, immunization rates in this specific patient population remain suboptimal, due in part to uncertainty about their efficacy or safety under these clinical situations. To address this concern, a multidisciplinary group of Canadian physicians with expertise in dermatology, gastroenterology, infectious diseases and rheumatology developed evidence-based clinical guidelines on vaccinations featuring 13 statements that are aimed at reducing the risk of preventable infections in individuals exposed to immunosuppressive agents.



November 15, 2019 at 8:13 am

Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America.

Am J Respir Crit Care Med. October 1, 2019  V.200 N.7  e45-e67.

Metlay JP, Waterer GW, Long AC, Anzueto A, Brozek J, Crothers K, et al.


This document provides evidence-based clinical practice guidelines on the management of adult patients with community-acquired pneumonia.


A multidisciplinary panel conducted pragmatic systematic reviews of the relevant research and applied Grading of Recommendations, Assessment, Development, and Evaluation methodology for clinical recommendations.


The panel addressed 16 specific areas for recommendations spanning questions of diagnostic testing, determination of site of care, selection of initial empiric antibiotic therapy, and subsequent management decisions. Although some recommendations remain unchanged from the 2007 guideline, the availability of results from new therapeutic trials and epidemiological investigations led to revised recommendations for empiric treatment strategies and additional management decisions.


The panel formulated and provided the rationale for recommendations on selected diagnostic and treatment strategies for adult patients with community-acquired pneumonia.


Este documento proporciona pautas de práctica clínica basadas en evidencia sobre el manejo de pacientes adultos con NAC.


Un panel multidisciplinario realizó revisiones sistemáticas pragmáticas de la investigación relevante y aplicó la metodología de calificación de recomendaciones, evaluación, desarrollo y evaluación para recomendaciones clínicas.


El panel abordó 16 áreas específicas para recomendaciones que abarcan preguntas sobre pruebas de diagnóstico, determinación del sitio de atención, selección de terapia ATB empírica inicial y decisiones de manejo posteriores. Aunque algunas recomendaciones permanecen sin cambios con respecto a la guía de 2007, la disponibilidad de resultados de nuevos ensayos terapéuticos e investigaciones epidemiológicas condujo a recomendaciones revisadas para estrategias de tratamiento empírico y decisiones de manejo adicionales.


El panel formuló y proporcionó la justificación de las recomendaciones sobre estrategias seleccionadas de diagnóstico y tratamiento para pacientes adultos con NAC.



November 15, 2019 at 7:59 am

British Thoracic Society community acquired pneumonia guideline and the NICE pneumonia guideline: how they fit together.

BMJ Open Respir Res. May 13, 2015 V.2 N.1 :e000091. doi: 10.1136/bmjresp-2015-000091.

Lim WS1, Smith DL2, Wise MP3, Welham SA4.

Author information

1 Department of Respiratory Medicine , Nottingham City Hospital , Nottingham , UK.

2 Southmead Hospital , North Bristol Lung Centre , Bristol , UK.

3 Department of Adult Critical Care , University Hospital of Wales , Cardiff , UK.

4 British Thoracic Society , London , UK.


The British Thoracic Society (BTS) guideline for the management of adults with community acquired pneumonia (CAP) published in 2009 was compared with the 2014 National Institute for Health and Care Excellence (NICE) Pneumonia Guideline. Of the 36 BTS recommendations that overlapped with NICE recommendations, no major differences were found in 31, including those covering key aspects of CAP management: timeliness of diagnosis and treatment, severity assessment and empirical antibiotic choice. Of the five BTS recommendations where major differences with NICE were identified, one related to antibiotic duration in low and moderate severity CAP, two to the timing of review of patients and two to legionella urinary antigen testing.


November 13, 2019 at 7:17 am

Diagnosis and Treatment of Adults with Community-acquired Pneumonia

Am J Respir Crit Care Med October 1, 2019 V.200 N.7 P.e45–e67

An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America



November 10, 2019 at 11:36 am

Effect of procalcitonin-guided antibiotic treatment on clinical outcomes in intensive care unit patients with infection and sepsis patients: a patient-level meta-analysis of randomized trials.

Crit Care. 2018;22:191. 

Wirz Y, Meier MA, Bouadma L, et al.



November 10, 2019 at 11:35 am

Surviving Sepsis Campaign: International guidelines for management of sepsis and septic shock: 2016.

Crit Care Med. 2017;45:486-552. 

Rhodes A, Evans LE, Alhazzani W, et al.



November 10, 2019 at 11:33 am

Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the Infectious Diseases Society of America and the American Thoracic Society.

Clin Infect Dis. 2016;63:e61-e111. 

Kalil AC, Metersky ML, Klompas M, et al.



November 10, 2019 at 11:31 am

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