Posts filed under ‘Infecciones de transmision sexual’
Clin Infect Dis. (2010) 51 (2): e12-e15
Eyal Meltzer, Yechezkel Sidi, Gill Smolen, Menachem Banai, Svetlana Bardenstein, and Eli Schwartz
1Center for Geographic Medicine and Department of Medicine C, Tel Hashomer
2Microbiology Laboratory, The Chaim Sheba Medical Center, Tel Hashomer
3Sackler School of Medicine, Tel Aviv University, Tel Aviv
4Department of Bacteriology, Kimron Veterinary Institute Bet Dagan, Israel
Sexual transmission of brucellosis has rarely been reported in humans. We describe 2 cases of probable sexual transmission of Brucella from husband to wife. In 1 case, orchidoepididimitis existed, whereas in the other case, the presence of Brucella in the semen in the absence of genital symptoms was demonstrated by polymerase chain reaction.
N Engl J Med June 2016 V.374 P.2504-2506
To the Editor:
Resistance to all antimicrobial agents has developed in some Neisseria gonorrhoeae strains. Dual antimicrobial therapy (ceftriaxone plus azithromycin) is a recommended first-line empirical treatment in many countries.1-3 We describe treatment failure with dual therapy in a patient with gonorrhea….
Clinical Infectious Diseases Dec.2011 V.53 N.12 Suppl.3 S110-S128
Khalil G. Ghanem1 and Kimberly A. Workowski2,3
1Johns Hopkins University School of Medicine, Baltimore, Maryland
2National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention
3Emory University, Atlanta, Georgia
There are several important unanswered key questions in the management of adult syphilis. A systematic literature review was conducted and tables of evidence were constructed to answer these important questions. A single dose of 2.4 million units of benzathine penicillin G remains the drug of choice for managing early syphilis. Enhanced antibiotic therapy has not been shown to improve treatment outcomes, regardless of human immunodeficiency virus (HIV) status. Although additional data on the efficacy of azithromycin in treating early syphilis have emerged, reported increases in the prevalence of a mutation associated with azithromycin resistance precludes a recommendation for its routine use. Cerebrospinal fluid (CSF) examination should be performed in all persons with serologic evidence of syphilis infection and neurologic symptoms. In those persons with early syphilis who do not achieve a ≥4-fold serologic decline in their rapid plasma reagin (RPR) titers 6–12 months after adequate therapy and those with late latent infection who do not achieve a similar decline within 12–24 months, CSF examination should be considered. Among HIV-infected persons, CSF examination among all those with asymptomatic late latent syphilis is not recommended owing to lack of evidence that demonstrates clinical benefit. HIV-infected persons with syphilis of any stages whose RPR titers are ≥1:32 and/or whose CD4 cell counts are <350 cells/mm3 may be at increased risk for asymptomatic neurosyphilis. If CSF pleocytosis is evident at initial CSF examination, these examinations should be repeated every 6 months until the cell count is normal. Several important questions regarding the management of syphilis remain unanswered and should be a priority for future research.
Clinical Infectious Diseases Dec.2011 V.53 N.12 Suppl.3 S79-S83
Kenneth H. Mayer1,2
1Harvard Medical School, Beth Israel Deaconess Medical Center
2Fenway Institute, Fenway Health, Boston, Massachusetts
Men who have sex with men (MSM) have increased rates of human immunodeficiency virus (HIV) infection and sexually transmitted diseases (STDs) compared with demographically matched controls. The reasons for the disproportionate infection burden are complex, including biological, behavioral, and sociocultural factors. HIV and syphilis may often be coprevalent among MSM. The use of nucleic acid amplification testing has enhanced the ability to detect frequently asymptomatic gonococcal and chlamydial infections of the rectum and other sites. Lymphogranuloma proctitis outbreaks among MSM were noted in the developed world several years ago but have not been common recently. MSM are at increased risk for viral hepatitis and anal human papillomavirus disease. Preventive interventions include vaccination for the former and anal cytologic screening for the latter. Because of the diverse ways in which MSM may be exposed to STDs, it is essential for clinicians to obtain a thorough sexual history in a culturally competent manner.
Clinical Infectious Diseases Dec.2011 V.53 N.12 Suppl.3 S84-S91
Linda M. Gorgos1 and Jeanne M. Marrazzo2
1Infectious Disease Bureau, Public Health Division, New Mexico Department of Health, Santa Fe
2Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle
Women who have sex with women (WSW) are a diverse group with variations in sexual identity, sexual behaviors, sexual practices, and risk behaviors. WSW are at risk of acquiring bacterial, viral, and protozoal sexually transmitted infections (STIs) from current and prior partners, both male and female. Bacterial vaginosis is common among women in general and even more so among women with female partners. WSW should not be presumed to be at low or no risk for STIs based on sexual orientation, and reporting of same-sex behavior by women should not deter providers from considering and performing screening for STIs, including chlamydia, in their clients according to current guidelines. Effective delivery of sexual health services to WSW requires a comprehensive and open discussion of sexual and behavioral risks, beyond sexual identity, between care providers and their female clients.
Emerging Infectious Diseases June 2016 V.22 N.6
To the Editor:
Antimicrobial resistance in Neisseria gonorrhoeae is increasing globally. In recent years, gonococcal strains with resistance to the extended-spectrum cephalosporin (ESC) ceftriaxone have been reported from many countries (1). In South America, 7 ceftriaxone-resistant strains (MICs >0.25 μg/mL) were reported from Brazil in 2007; however, these isolates have not been characterized (2). Emergence of cephalosporin-resistant gonorrhea would substantially limit treatment options and represent a major public health concern. We report an N. gonorrhoeae isolate in Argentina that was resistant to ceftriaxone and cefixime…..
2016-06 Neisseria gonorrhoeae Resistant to Ceftriaxone and Cefixime, Argentina EID