Posts filed under ‘Infecciones de transmision sexual’

Case of secondary syphilis presenting with unusual complications: syphilitic proctitis, gastritis, and hepatitis.

J Clin Microbiol. 2011 Dec;49(12):4394-6.

Adachi E1, Koibuchi T, Okame M, Sato H, Imai K, Shimizu S, Tsurita G, Oyaizu N, Iwamoto A, Fujii T.

Author information

1Department of Infectious Diseases and Applied Immunology, Research Hospital of The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

Abstract

We report the first known case of syphilis with simultaneous manifestations of proctitis, gastritis, and hepatitis. The diagnosis of syphilitic proctitis and gastritis was established by the demonstration of spirochetes with anti-Treponema pallidum antibody staining in biopsy specimens. Unusual manifestations of secondary syphilis completely resolved after 4 weeks of antibiotic therapy.

PDF

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233005/pdf/zjm4394.pdf

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December 11, 2016 at 12:17 pm

Editor’s Choice – The Molecular Epidemiology and Antimicrobial Resistance of Neisseria gonorrhoeae in Australia: A Nationwide Cross-Sectional Study, 2012

Clinical Infectious Diseases December 15, 2016 V.63 N.12 P.1591-1598

Ella Trembizki, Handan Wand, Basil Donovan, Marcus Chen, Christopher K. Fairley, Kevin Freeman, Rebecca Guy, John M. Kaldor, Monica M. Lahra, Andrew Lawrence, Colleen Lau, Julie Pearson, David G. Regan, Nathan Ryder, Helen Smith, Kerrie Stevens, Jiunn-Yih Su, James Ward, and David M. Whiley

1UQ Centre for Clinical Research, The University of Queensland, Brisbane

2Kirby Institute, UNSW Australia, Sydney

3Sydney Sexual Health Centre, Sydney Hospital, New South Wales

4Melbourne Sexual Health Centre, Alfred Health, Carlton

5Central Clinical School Monash University, Melbourne, Victoria

6Microbiology Laboratory, Pathology Department, Royal Darwin Hospital, Northern Territory

7WHO Collaborating Centre for STD, Microbiology Department, South Eastern Area Laboratory Services, Prince of Wales Hospital, Sydney, New South Wales

8Microbiology and Infectious Diseases Department, Women’s and Children’s Hospital, North Adelaide, South Australia

9Department of Global Health, Research School of Population Health, The Australian National University, Canberra, Australian Capital Territory

10PathWest Laboratory Medicine-WA, Royal Perth Hospital, Western Australia

11HNE Sexual Health, Hunter New England Local Health District, New South Wales

12Public Health Microbiology, Communicable Disease, Queensland Health Forensic and Scientific Services, Archerfield

13Microbiological Diagnostic Unit, Public Health Laboratory, Department of Microbiology and Immunology, The University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Victoria

14Sexual Health and Blood Borne Virus Unit, Centre for Disease Control, Darwin, Northern Territory

15South Australian Health and Medical Research Institute, Adelaide, South Australia

16Pathology Queensland Central Laboratory, Herston, Australia

Background

Antimicrobial resistance (AMR) by Neisseria gonorrhoeae is considered a serious global threat.

Methods

In this nationwide study, we used MassARRAY iPLEX genotyping technology to examine the epidemiology of N. gonorrhoeae and associated AMR in the Australian population. All available N. gonorrhoeae isolates (n = 2452) received from Australian reference laboratories from January to June 2012 were included in the study. Genotypic data were combined with phenotypic AMR information to define strain types.

Results

A total of 270 distinct strain types were observed. The 40 most common strain types accounted for over 80% of isolates, and the 10 most common strain types accounted for almost half of all isolates. The high male to female ratios (>94% male) suggested that at least 22 of the top 40 strain types were primarily circulating within networks of men who have sex with men (MSM). Particular strain types were also concentrated among females: two strain types accounted for 37.5% of all isolates from females. Isolates harbouring the mosaic penicillin binding protein 2 (PBP2)—considered a key mechanism for cephalosporin resistance—comprised 8.9% of all N. gonorrhoeae isolates and were primarily observed in males (95%).

Conclusions

This large scale epidemiological investigation demonstrated that N. gonorrhoeae infections are dominated by relatively few strain types. The commonest strain types were concentrated in MSM in urban areas and Indigenous heterosexuals in remote areas, and we were able to confirm a resurgent epidemic in heterosexual networks in urban areas. The prevalence of mosaic PBP2 harboring N. gonorrhoeae strains highlight the ability for new N. gonorrhoeae strains to spread and become established across populations.

PDF

https://cid.oxfordjournals.org/content/63/12/1591.full.pdf+html

December 11, 2016 at 12:03 pm

Likely sexual transmission of Zika virus from a man with no symptoms of infection — Maryland, 2016

MMWR Morb Mortal Wkly Rep September 2, 2016  V.65 N.34 P.915–916

Brooks RB et al

In June 2016, the Maryland Department of Health and Mental Hygiene (DHMH) was notified of a nonpregnant woman who sought treatment for a subjective fever and an itchy rash, which was described as maculopapular by her provider. Laboratory testing at the Maryland DHMH Laboratories Administration confirmed Zika virus infection. Case investigation revealed that the woman had not traveled to a region with ongoing transmission of Zika virus, but did have sexual contact with a male partner who had recently traveled to the Dominican Republic. The male partner reported exposure to mosquitoes while traveling, but no symptoms consistent with Zika virus infection either before or after returning to the United States. The woman reported no other sex partners during the 14 days before onset of her symptoms and no receipt of blood products or organ transplants….

PDF

http://www.cdc.gov/mmwr/volumes/65/wr/pdfs/mm6534e2.pdf

September 19, 2016 at 8:08 am

Mycoplasma genitalium Prevalence, Coinfection, and Macrolide Antibiotic Resistance Frequency in a Multicenter Clinical Study Cohort in the United States

Journal of Clinical Microbiology September 2016 V.54 N.9 P.2278-2283

Damon Getman, Alice Jiang, Meghan O’Donnell, and Seth Cohen

Damon Getmana, Alice Jianga, Meghan O’Donnella and Seth Cohenb*

aHologic, Inc., San Diego, California, USA

bOccidental College, Los Angeles, California, USA

Patel, Editor

Mayo Clinic

The prevalence rates of Mycoplasma genitalium infections and coinfections with other sexually transmitted organisms and the frequency of a macrolide antibiotic resistance phenotype were determined in urogenital specimens collected from female and male subjects enrolled in a multicenter clinical study in the United States. Specimens from 946 subjects seeking care from seven geographically diverse clinical sites were tested for M. genitalium and for Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis. Sequencing was used to assess macrolide antibiotic resistance among M. genitalium-positive subjects. M. genitalium prevalence rates were 16.1% for females and 17.2% for males. Significant risk factors for M. genitalium infections were black race, younger age, non-Hispanic ethnicity, and female symptomatic status. Female M. genitalium infections were significantly more prevalent than C. trachomatis and N. gonorrhoeae infections, while the M. genitalium infection rate in males was significantly higher than the N. gonorrhoeae and T. vaginalis infection rates. The macrolide-resistant phenotype was found in 50.8% of females and 42% of males. These results show a high prevalence of M. genitalium single infections, a lower prevalence of coinfections with other sexually transmitted organisms, and high rates of macrolide antibiotic resistance in a diverse sample of subjects seeking care across a wide geographic area of the United States.

PDF

http://jcm.asm.org/content/54/9/2278.full.pdf+html

September 1, 2016 at 2:24 pm

Update: Interim Guidance for Health Care Providers Caring for Pregnant Women with Possible Zika Virus Exposure — United States, July 2016

MMWR Morb Mortal Wkly Rep 2016;65(Early Release)

Titilope Oduyebo, MD; Irogue Igbinosa, MD; Emily E. Petersen, MD; et al.

CDC has updated its interim guidance for health care providers in the United States caring for pregnant women with possible Zika virus exposure, based on emerging data indicating Zika virus RNA can be detected for prolonged periods in some pregnant women. To increase the proportion of pregnant women with Zika virus infection who receive a definitive diagnosis, this guidance includes recommendations to expand real-time reverse transcription–polymerase chain reaction testing.

PDF

http://www.cdc.gov/mmwr/volumes/65/wr/pdfs/mm6529e1.pdf

July 26, 2016 at 8:27 am

Suspected Female-to-Male Sexual Transmission of Zika Virus — New York City, 2016

MMWR Morb Mortal Wkly Rep. Published online July 15, 2016

Alexander Davidson, MPH1; Sally Slavinski, DVM1; Kendra Komoto1; Jennifer Rakeman, PhD1; Don Weiss, MD1

1New York City Department of Health and Mental Hygiene, New York.

A routine investigation by the New York City (NYC) Department of Health and Mental Hygiene (DOHMH) identified a nonpregnant woman in her twenties who reported she had engaged in a single event of condomless vaginal intercourse with a male partner the day she returned to NYC (day 0) from travel to an area with ongoing Zika virus transmission. She had headache and abdominal cramping while in the airport awaiting return to NYC. The following day (day 1) she developed fever, fatigue, a maculopapular rash, myalgia, arthralgia, back pain, swelling of the extremities, and numbness and tingling in her hands and feet. In addition, on day 1, the woman began menses that she described as heavier than usual. On day 3 she visited her primary care provider who obtained blood and urine specimens. Zika virus RNA was detected in both serum and urine by real-time reverse transcription–polymerase chain reaction (rRT-PCR) performed at the DOHMH Public Health Laboratory using a test based on an assay developed at CDC (1). The results of serum testing for anti-Zika virus immunoglobulin M (IgM) antibody performed by the New York State Department of Health Wadsworth Center laboratory was negative using the CDC Zika IgM antibody capture enzyme-linked immunosorbent assay (Zika MAC-ELISA) (2).

FULL TEXT

http://www.cdc.gov/mmwr/volumes/65/wr/mm6528e2.htm?s_cid=mm6528e2_w

PDF

http://www.cdc.gov/mmwr/volumes/65/wr/pdfs/mm6528e2.pdf

July 15, 2016 at 3:17 pm

Sexually Transmitted Brucellosis in Humans

Clin Infect Dis. (2010) 51 (2): e12-e15

Eyal Meltzer, Yechezkel Sidi, Gill Smolen, Menachem Banai, Svetlana Bardenstein, and Eli Schwartz

1Center for Geographic Medicine and Department of Medicine C, Tel Hashomer

2Microbiology Laboratory, The Chaim Sheba Medical Center, Tel Hashomer

3Sackler School of Medicine, Tel Aviv University, Tel Aviv

4Department of Bacteriology, Kimron Veterinary Institute Bet Dagan, Israel

Sexual transmission of brucellosis has rarely been reported in humans. We describe 2 cases of probable sexual transmission of Brucella from husband to wife. In 1 case, orchidoepididimitis existed, whereas in the other case, the presence of Brucella in the semen in the absence of genital symptoms was demonstrated by polymerase chain reaction.

PDF

http://cid.oxfordjournals.org/content/51/2/e12.full.pdf+html

July 8, 2016 at 9:57 am

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